Navegação Technical documents and research evidence on COVID-19 por título
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Efficacy and safety of umifenovir for coronavirus disease 2019 (COVID‐19): A systematic review and meta‐analysis
(2020-07-03)Background: We conducted this systemic review and meta‐analysis in an attempt to evaluate the efficacy and safety of umifenovir in COVID‐19. Methods: We searched PubMed, Web of Science, Embase, Cochrane Library, CNKI and ... -
Efficacy of Chloroquine or Hydroxychloroquine in COVID-19 Patients: A Systematic Review and Meta-Analysis
(2020-07-15)Background: The antimalarial agents, chloroquine (CQ) and hydroxychloroquine (HCQ) show promising SARS-CoV-2 anti-viral activity in vitro; however, clinical studies have reported conflicting results. We sought to systematically ... -
Efficacy of chloroquine versus lopinavir/ritonavir in mild/general COVID-19 infection: a prospective, open-label, multicenter, randomized controlled clinical study
(2020-07-08)Background: The outbreak of COVID-19 (caused by SARS-Cov-2) is very serious, and no effective antiviral treatment has yet been confirmed. The adage “old drug, new trick” in this context may suggest the important therapeutic ... -
Efficacy of Lopinavir/Ritonavir Compared With Standard Care for Treatment of Coronavirus Disease 2019 (COVID-19): A Systematic Review
(2020-10-29)Background: Coronavirus disease 2019 (COVID-19) is a newly discovered multi-organ disease caused by the novel coronavirus SARS-CoV-2. Currently, there are no official guidelines on the pharmacological treatment of COVID-19. ... -
Efficacy of remdesivir in COVID-19 patients with a simulated two-arm controlled study
(2020-05-08)While the recent study on the compassionate use of remdesivir for COVID-19 patients has shown a 68% clinical improvement7 it is a one-arm study that renders the evaluation of the efficacy in reducing death and the length ... -
Efficient Prevalence Estimation and Population Screening for SARS-CoV-2
(2020-05-22)The testing capacity for SARS-CoV-2 using RT-PCR analyses can be substantially increased by using pooling techniques. Here we discuss two important consequences of this. First, prevalence estimation can be done with a very ... -
El Niño and climate change--contributing factors in the dispersal of Zika virus in the Americas?
(2016-06)In their letter, Isaac I Bogoch and colleagues (Jan 23, p 335)1 anticipated the international spread of Zika virus from Brazil through air traffic. Permissive climatic conditions for Aedes mosquitoes might have contributed ... -
Electron micrographs of erythrocytes from Swiss albino mice infected with Zika virus
(1953)The original source for this document may be restricted, preventing outside readers from accessing the content, or may no longer be available. Therefore, users need to use other resources to retrieve this information. -
Electronic Personal Protective Equipment: A Strategy to Protect Emergency Department Providers in the Age of COVID-19
(2020-04-02)[Abstract]. Emergent policy changes related to telemedicine and the Emergency Medical Treatment and Labor Act (EMTALA) during the novel coronavirus pandemic (COVID-19) have created opportunities for technology-based clinical ... -
Elementary spatial structures and dispersion of COVID-19: health geography directing responses to public health emergency in Sao Paulo State, Brazil
(2020-05-01)Public health policies to contain the spread of COVID-19 rely mainly on non-pharmacological measures. Those measures, especially social distancing, are a challenge for developing countries, such as Brazil. In Sao Paulo, ... -
Elevated RDW is Associated with Increased Mortality Risk in COVID-19
(2020-05-09)Abstract Background Coronavirus disease 2019 (COVID19) is an acute respiratory illness with a high rate of hospitalization and mortality. Prognostic biomarkers are urgently needed. Red blood cell distribution width (RDW), ... -
Emergence of a Novel Coronavirus (COVID-19): Protocol for Extending Surveillance Used by the Royal College of General Practitioners Research and Surveillance Centre and Public Health England
(2020-04-02)[Abstract]. Background: The Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC) and Public Health England (PHE) have successfully worked together on the surveillance of influenza and other ... -
Emergence of Congenital Zika Syndrome: Viewpoint From the Front Lines
(2016-06)The original source of this document may be restricted, preventing external readers from accessing the content, or it may no longer be available. Therefore, users need to use other resources to retrieve this information. -
Endocrinology in the time of COVID-19: Management of pituitary tumours
(2020-05-01)Patients with pituitary tumours, ensuing hormonal abnormalities and mass effects are usually followed in multidisciplinary pituitary clinics and can represent a management challenge even during times of non-pandemic. The ... -
Enhancing COVID-19 Mortality Surveillance in Latin America and the Caribbean through All-Cause Mortality Surveillance, May 2020
(2020-06-18)The purpose of this document is to provide guidance to countries of Latin America and the Caribbean (LAC) on improving COVID-19 mortality surveillance.1 The document expands on methods for the analysis of all-cause mortality ... -
Ensuring health equity during the COVID-19 pandemic: the role of public health infrastructure
(2020-06)[ABSTRACT]. The COVID-19 pandemic has significantly stressed public health systems around the world and exposed the gaps in health care for underserved and vulnerable populations. In the context of the social determinants ... -
Enteral, parenteral nutrition and their combination for adults in the intensive care unit
(2020-03-17)What is this? Some patients with COVID-19 will become critically ill and need treatment in an intensive care unit (ICU). This may interrupt their feeding routines and reduce appetite or increase nausea and vomiting, leading ... -
Entry routes for Zika virus in Brazil after 2014 world cup: New possibilities
(2016)In early 2015 it was reported several cases of Dengue and Chikungunya virus infections in various Brazilian states. Some states have been reported Zika virus cases has symptoms very similar to the symptoms of Dengue. A ... -
The Epidemic of Zika Virus-Related Microcephaly in Brazil: Detection, Control, Etiology, and Future Scenarios
(2016-06)We describe the epidemic of microcephaly in Brazil, its detection and attempts to control it, the suspected causal link with Zika virus infection during pregnancy, and possible scenarios for the future. In October 2015, ...