Browsing Technical documents and research evidence on COVID-19 by Title
Now showing items 993-1012 of 1749
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Methods of An Open-Label Proof-Of-Concept Trial of Intravenous Valproic Acid for Severe COVID-19
(2020-05-01)Background: Coronavirus disease 2019 (COVID-19) is the systemic entity caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that may cause death through severe atypical pneumonia and acute lung injury. ... -
Mexico: Lessons learned from the 2009 pandemic that help us fight COVID-19
(2020-05-06)In April 2009, Mexican, American, and Canadian authorities announced a novel influenza that became the first pandemic of the century. We report on lessons learned in Mexico. The Mexican Pandemic Influenza Preparedness and ... -
Microcephaly and Zika virus: neonatal neuroradiological aspects
(2016-06)PURPOSE: The aim of this study is to describe some radiological features in the newborns with microcephaly caused by Zika virus infection during pregnancy. METHODS: We radiologically analyzed 13 cases of newborns with ... -
Microcephaly associated with maternal Zika virus infection
(2016-06)The original source of this document may be restricted, which can prevent outside readers from having access to it. Also, it may be no longer available. In case of need, users need to use other resources to recover this ... -
Microcephaly in Brazil: how to interpret reported numbers?
(2016-06)Brazil is facing its first outbreak of Zika virus, particularly in the northeast region. Most cases of Zika virus infection are self-limited and without sequelae, but there have been clusters of cases of microcephaly in ... -
Microcephaly in Infants, Pernambuco State, Brazil, 2015
(2016-07)We studied the clinical characteristics for 104 infants born with microcephaly in the delivery hospitals of Pernambuco State, Brazil, during 2015. Testing is ongoing to exclude known infectious causes. However, microcephaly ... -
Microcephaly in northeastern Brazil: a review of 16 208 births between 2012 and 2015
(2016-06)A recent outbreak of microcephaly has been reported from Northeast Brazil. Neither its aetiology, nor its clinical significance has yet been fully established. A complication from an intrauterine infection with the Zika ... -
Model-based projections of Zika virus infections in childbearing women in the Americas
(2016-07)Zika virus is a mosquito-borne pathogen that is rapidly spreading across the Americas. Due to associations between Zika virus infection and a range of fetal maladies(1,2), the epidemic trajectory of this viral infection ... -
Modeling Return of the Epidemic: Impact of Population Structure, Asymptomatic Infection, Case Importation and Personal Contacts
(2020-05-01)Background: Proactive interventions have halted the pandemic of coronavirus infected disease in some regions. However, without reaching herd immunity, the return of epidemic is possible. We investigate the impact of ... -
Modeling the COVID-19 outbreak in Ecuador: Is it the right time to lift social distancing containment measures?
(2020-05-23)Objective. Model the effect of partial and full reversal of containment measures on COVID-19 morbidity and mortality in Ecuador. Methods. Susceptible, Infected, Recovered (SIR) models were used to simulate the transmission ... -
Modeling the epidemic dynamics and control of COVID-19 outbreak in China
(2020-03-11)Background. The coronavirus disease 2019 (COVID-19) is rapidly spreading in China and more than 30 countries over last two months. COVID-19 has multiple characteristics distinct from other infectious diseases, including ... -
Modelling of Systemic versus Pulmonary Chloroquine Exposure in Man for COVID-19 Dose Selection
(2020-05-01)Chloroquine has attracted intense attention as a potential clinical candidate for prevention and treatment of COVID-19 based on reports of in-vitro efficacy against SARS-CoV-2. While the pharmacokinetic-pharmacodynamic ... -
Modes of transmission of virus causing COVID-19: implications for IPC precaution recommendations. Scientific brief, 27 March 2020
(2020-03-27)According to current evidence, COVID-19 virus is transmitted between people through respiratory droplets and contact routes. Droplet transmission occurs when a person is in in close contact (within 1 m) with someone who ... -
Modes of transmission of virus causing COVID-19:implications for IPC precaution recommendations. Scientific Brief, 29 March 2020
(2020-03-29)Modes of transmission of the COVID-19 virus: Respiratory infections can be transmitted through droplets of different sizes: when the droplet particles are >5-10 μm in diameter they are referred to as respiratory droplets, ... -
Modified telehealth for care of chronic wounds during the Coronavirus disease 2019 pandemic: A rapid literature review of alternative care modalities
(2020-09-09)Due to the changes in delivering medical care during the Coronavirus disease 2019 (COVID‐19) pandemic, such as the heavy reliance on telehealth, it is worth exploring if this is suitable when treating complex wounds. A ... -
Molecular Characterization of Three Zika Flaviviruses Obtained from Sylvatic Mosquitoes in the Central African Republic
(2014)Zika virus (ZIKV) is an emerging pathogen belonging to the Spondweni serocomplex within the genus Flavivirus. It has been isolated from several mosquito species. Two lineages of ZIKV have been defined by polyprotein homology. ... -
Molecular detection of SARS-CoV-2 using a reagent-free approach
(2020-05-02)Shortage of reagents and consumables required for the extraction and molecular detection of SARS-CoV-2 RNA in respiratory samples has led many laboratories to investigate alternative approaches for sample preparation. ... -
Molecular Evolution of Zika Virus during Its Emergence in the 20th Century
(2014)Zika virus (ZIKV) is a mosquito-borne flavivirus first isolated in Uganda in 1947. Although entomological and virologic surveillance have reported ZIKV enzootic activity in diverse countries of Africa and Asia, few human ... -
Molecular Mechanism of Evolution and Human Infection with SARS-CoV-2
(2020-04-10)The outbreak of a novel coronavirus, which was later formally named the severe acute respiratory coronavirus 2 (SARS-CoV-2), has caused a worldwide public health crisis. Previous studies showed that SARS-CoV-2 is highly ...