Survey of the first case of Zika virus disease in the mainland of China

Abstract

OBJECTIVE: To analyze epidemiological characteristics of the first laboratory confirmed case of Zika virus disease in the mainland China, and provide evidence for the prevention and control of the spread of Zika virus disease. METHODS: Epidemiological survey was conducted for the first suspect case of Zika virus disease in China, and medical observation was conducted for the close contacts. The nucleic acid detection of Zika virus was conducted with Real-time RT-PCR by using blood and urine samples collected from the cases. RESULTS: The first case of Zika virus disease was confirmed. The case was cured and discharged on 18(th) day after the onset. The blood sample on 10(th) day after the onset and urine samples on 11-13(th) days after the onset were all positive for Zika virus. The case had the history of mosquito bites in the endemic country before the onset. The close contacts showed no Zika virus disease-like symptoms during the medical observation period. CONCLUSION: The case reported by Jiangxi province was the first imported case of Zika virus disease in the mainland of China. The infection was related with the mosquito bites in Venezuela where Zika virus disease in endemic.