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Extracorporeal Membrane Oxygenation in COVID-19 Treatment: a Systematic Literature Review
dc.contributor.author | Oliveira, Tatiana Farias de et al. | |
dc.date.accessioned | 2021-05-14T21:32:04Z | |
dc.date.available | 2021-05-14T21:32:04Z | |
dc.date.issued | 2020-12-23 | |
dc.identifier.uri | https://doi.org/10.21470/1678-9741-2020-0397 | en_US |
dc.identifier.uri | https://hdl.handle.net/20.500.12663/2610 | |
dc.description.abstract | Introduction: The present study intends to systematically review the literature on the use of extracorporeal membrane oxygenation (ECMO) in patients with coronavirus disease 2019 (COVID-19). Methods: The research was carried out according to the recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analyzes (PRISMA). Studies were selected from PubMed/MEDLINE and LILACS databases between December 2019 and May 17 2020, using the descriptors "ECMO AND COVID-19", "Extracorporeal Membrane Oxygenation AND COVID-19", "ECLS AND COVID-19", and "Extracorporeal Life Support AND COVID-19". Exclusion criteria were government epidemiological bulletins, comments, literature reviews, and articles without full access to content. Results: Two hundred and thirty-three scientific productions were found, however only 18 did not met the exclusion criteria and could be included in this study, amouting to a total of 911 patients - 624 (68.5%) men, 261 (28.6%) women, and 26 (2.8%) without sex information. The mean age of the patients was 53.7 years. ECMO was necessary in 274 (30.1%) people (200 [73%] submitted to venovenous ECMO, nine [3.3%] to veno-arterial ECMO, and seven [2.5%] moved between these two types or needed a more specific ECMO according to the disease prognosis). Five studies did not specify the type of ECMO used, amounting 57 (20.8%) patients. Five patients (1.8%) were discharged, 77 (28.1%) died, 125 (45.6%) remained hospitalized until publication time of their respective studies, and 67 patients (24.4%) had no outcome information. Conclusion: It is evident that more research, covering larger populations, must be carried out in order to clearly elucidate the role of ECMO in the treatment of COVID-19. | en_US |
dc.language | English | en_US |
dc.subject | COVID-19 | en_US |
dc.subject | Coronavirus Infections | en_US |
dc.subject | Extracorporeal Membrane Oxygenation | en_US |
dc.subject | Patient Discharge | en_US |
dc.subject | Betacoronavirus | en_US |
dc.subject | Oxygenation | en_US |
dc.title | Extracorporeal Membrane Oxygenation in COVID-19 Treatment: a Systematic Literature Review | en_US |
eihealth.country | Others | en_US |
eihealth.category | Candidate therapeutics RD | en_US |
eihealth.type | Published Article | en_US |
eihealth.maincategory | Save Lives / Salvar Vidas | en_US |
dc.relation.ispartofjournal | Brazilian Journal of Cardiovascular Surgery | en_US |
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