dc.contributor.author | Tuty Kuswardhani, R.A. et al. | |
dc.date.accessioned | 2021-01-06T18:15:13Z | |
dc.date.available | 2021-01-06T18:15:13Z | |
dc.date.issued | 2020-10-28 | |
dc.identifier.uri | https://doi.org/10.1016/j.dsx.2020.10.022 | en_US |
dc.identifier.uri | https://hdl.handle.net/20.500.12663/2465 | |
dc.description.abstract | Background and aims: The ongoing COVID-19 pandemic is disproportionately affecting patients with comorbidities. Therefore, thorough comorbidities assessment can help establish risk stratification of patients with COVID-19, upon hospital admission. Charlson Comorbidity Index (CCI) is a validated, simple, and readily applicable method of estimating the risk of death from comorbid disease and has been widely used as a predictor of long-term prognosis and survival. Methods: We performed a systematic review and meta-analysis of CCI score and a composite of poor outcomes through several databases. Results: Compared to a CCI score of 0, a CCI score of 1–2 and CCI score of ≥3 was prognostically associated with mortality and associated with a composite of poor outcomes. Per point increase of CCI score also increased mortality risk by 16%. Moreover, a higher mean CCI score also significantly associated with mortality and disease severity. Conclusion: CCI score should be utilized for risk stratifications of hospitalized COVID-19 patients. | en_US |
dc.language | English | en_US |
dc.subject | COVID-19 | en_US |
dc.subject | Coronavirus | en_US |
dc.subject | Coronavirus Infections | en_US |
dc.subject | Infectious Diseases | en_US |
dc.subject | Mortality | en_US |
dc.subject | Respiration, Artificial | en_US |
dc.title | Charlson comorbidity index and a composite of poor outcomes in COVID-19 patients: A systematic review and meta-analysis | en_US |
eihealth.country | Others | en_US |
eihealth.category | Ethical considerations for research | en_US |
eihealth.type | Published Article | en_US |
eihealth.maincategory | Save Lives / Salvar Vidas | en_US |
dc.relation.ispartofjournal | Diabetes & Metabolic Syndrome: Clinical Research & Reviews | en_US |