Mostrar el registro sencillo del ítem
Characterisation of clinical, laboratory and imaging factors related to mild vs. severe covid-19 infection: a systematic review and meta-analysis
dc.contributor.author | Wu, Xiaomei et al. | |
dc.date.accessioned | 2020-09-23T19:50:31Z | |
dc.date.available | 2020-09-23T19:50:31Z | |
dc.date.issued | 2020-08 | |
dc.identifier.uri | https://doi.org/10.1080/07853890.2020.1802061 | en_US |
dc.identifier.uri | https://hdl.handle.net/20.500.12663/2263 | |
dc.description.abstract | Background: Early detection of disease progression associated with severe COVID-19, and access to proper medical care lowers fatality rates of severe cases. Currently, no studies had systematically examined the variables in detecting severe COVID-19. Method: Systematic searching of electronic databases identified observational studies which recruited participants with confirmed COVID-19 infection who were divided into different groups according to disease severity were identified. Results: To analysis 41 studies with 5064 patients were included.Patients who are elderly (SMD, 1.90; 95% CI, 1.01 to 2.8), male (OR, 1.71; 95% CI, 1.39 to 2.11) and have comorbidities or flu-like symptoms were significantly associated with the development to severe cases. Severe cases were associated with significant increased WBC (OR, 5.83; 95% CI, 2.76 to 12.32), CRP (OR, 3.62; 95% CI, 1.62 to 8.03), D-dimer (SMD, 1.69; 95% CI, 1.09 to 2.28), AST (OR, 4.64; 95% CI, 3.18 to 6.77) and LDH (OR, 7.94; 95% CI, 2.09 to 30.21). CT manifestation of bilateral lung involvement (OR, 4.55; 95% CI, 2.17 to 9.51) was associated with the severe cases. Conclusions and Relevance: Our findings offer guidance for a wide spectrum of clinicians to early identify severe COVID-19 patients, transport to specialised centres, and initiate appropriate treatment. | en_US |
dc.language | English | en_US |
dc.subject | COVID-19 | en_US |
dc.subject | Meta-Analysis | en_US |
dc.subject | Coronavirus Infections | en_US |
dc.subject | Systematic Review | en_US |
dc.subject | Coronavirus | en_US |
dc.title | Characterisation of clinical, laboratory and imaging factors related to mild vs. severe covid-19 infection: a systematic review and meta-analysis | en_US |
eihealth.country | Others | en_US |
eihealth.category | Virus: natural history, transmission and diagnostics | en_US |
eihealth.category | Clinical characterization and management | en_US |
eihealth.category | Health systems and services | en_US |
eihealth.type | Published Article | en_US |
eihealth.maincategory | Save Lives / Salvar Vidas | en_US |
dc.relation.ispartofjournal | Ann. Med | en_US |
Ficheros en el ítem
Ficheros | Tamaño | Formato | Ver |
---|---|---|---|
No hay ficheros asociados a este ítem. |