dc.contributor.author | Lim, Michael Anthonius | |
dc.contributor.author | Pranata, Raymond | |
dc.date.accessioned | 2020-10-02T13:37:38Z | |
dc.date.available | 2020-10-02T13:37:38Z | |
dc.date.issued | 2020-09-17 | |
dc.identifier.uri | https://doi.org/10.1016/j.jcot.2020.09.015 | en_US |
dc.identifier.uri | https://hdl.handle.net/20.500.12663/2298 | |
dc.description.abstract | Introduction: This systematic review and meta-analysis aimed to evaluate the prevalence of coronavirus disease 2019 (COVID-19) and its impact on mortality in patients with hip fracture. Methods: We performed a systematic literature search in PubMed, Cochrane Central Database, and medRvix from inception up to July 13, 2020 on research articles that enrolled hip fracture patients who had information on COVID-19 and clinically validated definition of death. Results: A total of 984 participants from 6 studies were included in our study. The pooled prevalence of COVID-19 was 9% [95% CI: 7–11%]. The mortality rate in patients with concomitant hip fracture and COVID-19 was found to be 36% (95% CI: 26–47%), whereas the mortality rate in hip fracture without COVID-19 is 2% (95% CI: 1–3%). Meta-analysis showed that COVID-19 was associated with a seven-fold increase in risk (RR 7.45 [95% CI: 2.72, 20.43], p < 0.001; I2: 68.6%) of mortality in patients with hip fracture. Regression-based Harbord’s test showed no indication of small-study effects (p = 0.06). Conclusion: The present meta-analysis showed that COVID-19 increased the risk of mortality in patients with hip fracture. | en_US |
dc.language | English | en_US |
dc.subject | COVID-19 | en_US |
dc.subject | Hip Fractures | en_US |
dc.subject | Femoral Fractures | en_US |
dc.subject | Hip | en_US |
dc.subject | Mortality | en_US |
dc.subject | General Surgery | en_US |
dc.subject | Coronavirus | en_US |
dc.subject | Coronavirus Infections | en_US |
dc.subject | Infectious Diseases | en_US |
dc.title | Coronavirus disease 2019 (COVID-19) markedly increased mortality in patients with hip fracture – A systematic review and meta-analysis | en_US |
eihealth.country | Others | en_US |
eihealth.category | Clinical characterization and management | en_US |
eihealth.category | Health systems and services | en_US |
eihealth.type | Published Article | en_US |
eihealth.maincategory | Save Lives / Salvar Vidas | en_US |
dc.relation.ispartofjournal | Journal of Clinical Orthopaedics and Trauma | en_US |