dc.contributor.author | Iwasaki, Sumio et al. | |
dc.date.accessioned | 2020-06-16T17:21:54Z | |
dc.date.available | 2020-06-16T17:21:54Z | |
dc.date.issued | 2020-05-24 | |
dc.identifier.uri | https://doi.org/10.1101/2020.05.13.20100206 | en_US |
dc.identifier.uri | https://hdl.handle.net/20.500.12663/1760 | |
dc.description.abstract | We prospectively compared the efficacy of PCR detection of SARS-CoV-2 between paired nasopharyngeal and saliva samples in 76 patients including ten COVID-19 patients. The overall concordance rate of the virus detection between the two samples was 97.4% (95%CI, 90.8-99.7). Viral load was equivalent in COVID-19 patients, but the virus tended to disappear earlier in saliva at convalescent phase compared to nasopharyngeal samples. These results suggest that saliva is a reliable noninvasive alternative to nasopharyngeal swabs and facilitate widespread PCR testing in the face of shortages of swabs and protective equipment without posing a risk to healthcare workers. | en_US |
dc.language | English | en_US |
dc.subject | COVID-19 | en_US |
dc.subject | Coronavirus | en_US |
dc.subject | Betacoronavirus | en_US |
dc.subject | Polymerase Chain Reaction | en_US |
dc.subject | Saliva | en_US |
dc.subject | Nasopharynx | en_US |
dc.subject | Health Personnel | en_US |
dc.subject | Personal Protective Equipment | en_US |
dc.title | Comparison of SARS-CoV-2 detection in nasopharyngeal swab and saliva | en_US |
eihealth.country | Global (WHO/OMS) | en_US |
eihealth.category | Virus: natural history, transmission and diagnostics | en_US |
eihealth.type | Published Article | en_US |
eihealth.maincategory | Slow Spread / Reducir la Dispersión | en_US |
dc.relation.ispartofjournal | medRxiv | en_US |