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Viral RNA load as determined by cell culture as a management tool for discharge of SARS-CoV-2 patients from infectious disease wards: draft

 
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Date
2020-03
Author
La Scola, Bernard et al.
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Abstract
In a preliminary clinical study we observed that the combination of hydroxychloroquine and azithromycin was effective active against SARS-CoV-2 by shortening the duration of viral load in Covid-19 patients. It is of paramount importance to define when a treated patient can be considered as no longer contagious. Correlation between successful isolation of virus in cell culture and Ct value of quantitative RT-PCR targeting E-gene suggests that patients with Ct above 33-34 are not contagious and thus can be discharged from hospital care.
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https://www.mediterranee-infection.com/wp-content/uploads/2020/03/La-Scola-et-al.3-IHU-draft.pdf
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