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dc.contributor.authorEsquinas, Antonio M.
dc.contributor.authorPravinkumar, S. Egberten_US
dc.contributor.authorScala, Raffaeleen_US
dc.contributor.authorGay, Peteren_US
dc.contributor.authorSoroksky, Arieen_US
dc.contributor.authorGirault, Christopheen_US
dc.contributor.authorHan, Fangen_US
dc.contributor.authorHui, David S.en_US
dc.contributor.authorPapadakos, Peter J.en_US
dc.contributor.authorAmbrosino, Nicolinoen_US
dc.description.abstract[Abstract]. The aim of this article was to review the role of noninvasive ventilation (NIV) in acute pulmonary infectious diseases, such as severe acute respiratory syndrome (SARS), H1N1 and tuberculosis, and to assess the risk of disease transmission with the use of NIV from patients to healthcare workers. We performed a clinical review by searching Medline and EMBASE. These databases were searched for articles on “clinical trials” and “randomised controlled trials”. The keywords selected were non-invasive ventilation pulmonary infections, influenza-A (H1N1), SARS and tuberculosis. These terms were cross-referenced with the following keywords: health care workers, airborne infections, complications, intensive care unit and pandemic. The members of the International NIV Network examined the major results regarding NIV applications and SARS, H1N1 and tuberculosis. Cross-referencing mechanical ventilation with SARS yielded 76 studies, of which 10 studies involved the use of NIV and five were ultimately selected for inclusion in this review. Cross-referencing with H1N1 yielded 275 studies, of which 27 involved NIV. Of these, 22 were selected for review. Cross-referencing with tuberculosis yielded 285 studies, of which 15 involved NIV and from these seven were selected. In total 34 studies were selected for this review. NIV, when applied early in selected patients with SARS, H1N1 and acute pulmonary tuberculosis infections, can reverse respiratory failure. There are only a few reports of infectious disease transmission among healthcare workers.en_US
dc.subjectNoninvasive Ventilationen_US
dc.subjectSARS Virusen_US
dc.subjectSevere Acute Respiratory Syndromeen_US
dc.subjectInfluenza A Virus, H1N1 Subtypeen_US
dc.titleNoninvasive mechanical ventilation in high-risk pulmonary infections: a clinical reviewen_US
eihealth.categoryClinical characterization and managementen_US
eihealth.typePublished Articleen_US
eihealth.maincategorySave Lives / Salvar Vidasen_US
dc.relation.ispartofjournalEuropean Respiratory Reviewen_US
dc.contributor.corporatenameInternational NIV Networken_US

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