• English
    • español
    • português (Brasil)
  • English 
    • English
    • español
    • português (Brasil)
  • Login
View Item 
  •   COVID-19
  • Resources in English
  • Technical documents and research evidence on COVID-19
  • View Item
  •   COVID-19
  • Resources in English
  • Technical documents and research evidence on COVID-19
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

A Multi-centre, Adaptive, Randomized, Double-Blind, PlaceboControlled Clinical Trial of the Safety and Efficacy of Investigational Therapeutics for the Treatment of COVID-19 in Hospitalized Patients

 
Thumbnail
Author
World Health Organization
Metadata
Show full item record
Abstract
This is a multi-centre, adaptive, randomized, double-blind, placebo-controlled clinical trial to evaluate the efficacy and safety of investigational therapeutic agents in combination with standard-of care for the treatment of hospitalized patients with novel coronavirus disease (COVID-19). This Master Protocol is largely based on a series of deliberations of the WHO R&D Blueprint Clinical Trials Expert Group. The experts included international clinical trialists, coronavirus experts, regulatory and ethics experts and clinicians, including those treating COVID-19 patients. Based on those deliberations, experts at the National Institute of Allergy and Infectious Diseases (NIAID) at the US National Institutes of Health developed the full version of the protocol. The version was then further adjusted to facilitate its implementation internationally.
URI
https://www.who.int/blueprint/priority-diseases/key-action/multicenter-adaptive-RCT-of-investigational-therapeutics-for-COVID-19.pdf?ua=1
Collections
  • Technical documents and research evidence on COVID-19

Browse

AllCommunities & CollectionsBy Issue DateAuthorsTitlesCategorySubjectsThis CollectionBy Issue DateAuthorsTitlesCategorySubjects

My Account

LoginRegister

Pan American Health Organization
World Health Organization. Regional Office for the Americas
525 Twenty-third Street, N.W., Washington, D.C. 20037, United States of America

Content Disclaimer (Important notes about the material)

Links

  • WHO International Clinical Trial Registry Platform (ICTRP)
  • WHO Coronavirus disease R&D Blueprint
  • WHO Database of Publications on Coronavirus Disease
  • PAHO Coronavirus Disease
  • PAHO/BIREME Windows of Knowledge COVID-19
  • Evidence aid Coronavirus (COVID-19) resources

  • PAHO Digital Library (IRIS PAHO)
  • Virtual Health Library (VHL)
  • Global Index Medicus (GIM)