Browsing Technical documents and research evidence on COVID-19 by Title
Now showing items 656-675 of 1749
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Favipiravir versus Arbidol for COVID-19: A Randomized Clinical Trial
Importance: WHO has made the assessment that coronavirus disease 2019 (COVID-19) can be characterized as a pandemic. But there is no effective antiviral drug for COVID-19 so far. Objective: To compare the efficacy and ... -
Favipiravir versus other antiviral or standard of care for COVID-19 treatment: a rapid systematic review and meta-analysis
(2020-09-24)Background: The COVID-19 causing coronavirus is an enveloped RNA virus that utilizes an enzyme RNA dependent RNA polymerase for its replication. Favipiravir (FVP) triphosphate, a purine nucleoside analog, inhibits that ... -
The FDA-approved Drug Ivermectin inhibits the replication of SARS-CoV-2 in vitro
(2020-04-03)Although several clinical trials are now underway to test possible therapies, the worldwide response to the COVID-19 outbreak has been largely limited to monitoring/containment. We report here that Ivermectin, an FDA-approved ... -
Featuring COVID-19 cases via screening symptomatic patients with epidemiologic link during flu season in a medical center of central Taiwan
(2020-03-13)Background: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CO-V-2), was first reported in Wuhan, Hubei province, China has now rapidly spread over 50 countries. For the ... -
Febrile or Exanthematous Illness Associated with Zika, Dengue, and Chikungunya Viruses, Panama
(2016)The earliest clinical cases of Zika virus infection were reported from continental South America in 2015 (1), after which the virus spread rapidly through the Americas (2). Here we describe an investigation of febrile or ... -
Ferritin levels and COVID-19
(2020-06)[Extract]. Ferritin is a key mediator of immune dysregulation, especially under extreme hyperferritinemia, via direct immune-suppressive and pro-inflammatory effects, contributing to the cytokine storm1. It has been reported ... -
First Case of 2019 Novel Coronavirus in the United States
(2020-03-05)An outbreak of novel coronavirus (2019-nCoV) that began in Wuhan, China, has spread rapidly, with cases now confirmed in multiple countries. We report the first case of 2019-nCoV infection confirmed in the United States ... -
First case of imported Zika virus infection in Spain
(2016-06)We report a case of Zika virus (ZIKV) infection in a patient with diarrhea, fever, synovitis, non-purulent conjunctivitis, and with discreet retro-orbital pain, after returning from Colombia in January 2016. The patient ... -
First case of laboratory-confirmed Zika virus infection imported into Europe, November 2013
(2014)In November 2013, an acute Zika virus (ZIKV) infection was diagnosed in a German traveller returning from Thailand. The patient reported a clinical picture resembling dengue fever. Serological investigations revealed ... -
First Case of Zika Virus Infection in a Returning Canadian Traveler
(2014)A woman who recently traveled to Thailand came to a local emergency department with a fever and papular rash. She was tested for measles, malaria, and dengue. Positive finding for IgM antibody against dengue and a failure ... -
First Complete Genome Sequence of Zika Virus (Flaviviridae, Flavivirus) from an Autochthonous Transmission in Brazil
(2016-06)We report here the genome sequence of Zika virus, strain ZikaSPH2015, containing all structural and nonstructural proteins flanked by the 5' and 3' untranslated region. It was isolated in São Paulo state, Brazil, in 2015, ... -
First detection of autochthonous Zika virus transmission in a HIV-infected patient in Rio de Janeiro, Brazil
(2016)Since May 2015, Brazil's Ministry of Health has reported autochthonous transmission of Zika virus (ZIKV) in some states of the country. Simultaneous circulation of Dengue, Chikungunya and ZIKV in the country hinder both ... -
First Mildly Ill, Non-Hospitalized Case of Coronavirus Disease 2019 (COVID-19) Without Viral Transmission in the United States — Maricopa County, Arizona, 2020
(2020-04-02)[Abstract]. Background: Coronavirus disease 2019 (COVID-19) causes a range of illness severity. Mild illness has been reported, but whether illness severity correlates with infectivity is unknown. We describe the public ... -
First report of autochthonous transmission of Zika virus in Brazil
(2016)In the early 2015, several cases of patients presenting symptoms of mild fever, rash, conjunctivitis and arthralgia were reported in the northeastern Brazil. Although all patients lived in a dengue endemic area, molecular ... -
First report of Zika virus infection in a returned traveller from the Solomon Islands
(2016-06)A 33-year-old man returning from the Solomon Islands presented to an emergency department in Brisbane after 4 days of retro-orbital headache, fever, and myalgias, which had started 10 days into his journey. On examination, ... -
First-wave COVID-19 transmissibility and severity in China outside Hubei after control measures, and second-wave scenario planning: a modelling impact assessment
(2020-04-08)Background: As of March 18, 2020, 13415 confirmed cases and 120 deaths related to coronavirus disease 2019 (COVID-19) in mainland China, outside Hubei province—the epicentre of the outbreak—had been reported. Since late ... -
Forecasting COVID-19 impact on hospital bed-days, ICU-days, ventilatordays and deaths by US state in the next 4 months
(2020-03-26)Key Points Question: Assuming social distancing measures are maintained, what are the forecasted gaps in available health service resources and number of deaths from the COVID-19 pandemic for each state in the United States? ... -
Frequency of Long QT in Patients with SARS-CoV-2 Infection Treated with Hydroxychloroquine: A Meta-analysis
(2020-10-24)Introduction: Hydroxychloroquine (HCQ) has been proposed as a SARS-CoV-2 treatment but the frequency of long QT (LQT) during use is unknown. Objective: To conduct a meta-analysis of the frequency of LQT in patients with ... -
Frequency of routine testing for SARS-CoV-2 to reduce transmission among workers
(2020-05-06)Shelter-in-place policies have been considered effective in mitigating the transmission of the virus SARS-CoV-2. To end such policies, routine testing and self-quarantine of those testing positive for active infection have ...