Browsing Technical documents and research evidence on COVID-19 by Title
Now showing items 508-527 of 1749
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Echocardiographic Features of Cardiac Injury Related to COVID-19 and Their Prognostic Value: A Systematic Review
(2020-12-22)[Abstract]. Background: The available information on the echocardiographic features of cardiac injury related to the novel coronavirus disease 2019 (COVID-19) and their prognostic value are scattered in the different ... -
Editor’s commentary: Rapid reviews of PPE – an update
(2020-04-14)In early March 2020, as the COVID-19 crisis began to break in the UK, the Oxford Centre for Evidence-Based Medicine set up the COVID-19 Evidence Service (https://www.cebm.net/covid-19/). We invited questions from policymakers, ... -
Education interventions to improve healthcare workers’ adherence to Standard Precautions for the control of health care-associated infections
(2020-03-22)What is this? Standard Precautions, including using personal protective equipment (PPE) or adhering to safe handling of needles are essential for the prevention and spread of infections, such as COVID-19, in healthcare ... -
The effect of BCG vaccination on COVID-19 examined by a statistical approach: no positive results from the Diamond Princess and cross-national differences previously reported by world-wide comparisons are flawed in several ways
(2020-05-22)Recently, the controversial hypothesis that past BCG (Bacillus Calmette-Guerin) vaccination reduces infection or severity of COVID-19 has been proposed. The present study examined this hypothesis using statistical approaches ... -
Effect of Chloroquine, Hydroxychloroquine, and Azithromycin on the Corrected QT Interval in Patients With SARS-CoV-2 Infection
(2020-04-29)Background: The novel SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is responsible for the global coronavirus disease 2019 pandemic. Small studies have shown a potential benefit of chloroquine/hydroxychlor ... -
Effect of Colchicine vs Standard Care on Cardiac and Inflammatory Biomarkers and Clinical Outcomes in Patients Hospitalized With Coronavirus Disease 2019
(2020)Importance: Severe acute respiratory syndrome coronavirus 2 infection has evolved into a global pandemic. Low-dose colchicine combines anti-inflammatory action with a favorable safety profile. Objective: To evaluate the ... -
The effect of control strategies to reduce social mixing on outcomes of the COVID-19 epidemic in Wuhan, China: a modelling study
(2020-03-25)Background: In December, 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a novel coronavirus, emerged in Wuhan, China. Since then, the city of Wuhan has taken unprecedented measures in response to the ... -
The effect of corticosteroid treatment on patients with coronavirus infection: a systematic review and meta-analysis
(2020-03-31)Objectives: An outbreak of novel coronavirus in 2019 threatens the health of people, and there is no proven pharmacological treatment. Although corticosteroids were widely used during outbreaks of se- vere acute respiratory ... -
The effect of frailty on survival in patients with COVID-19 (COPE): a multicentre, European, observational cohort study
(2020-06-30)Background: The COVID-19 pandemic has placed unprecedented strain on health-care systems. Frailty is being used in clinical decision making for patients with COVID-19, yet the prevalence and effect of frailty in people ... -
Effect of Heat inactivation on Real-Time Reverse Transcription PCR of the SARS-COV-2 Detection
(2020-05-28)Background: Real-time reverse transcription PCR (rRT-PCR) is commonly used to diagnose SARS-CoV-2 infection. Heat inactivation prior to nucleic acid isolation may allow safe testing, while the effects of heat inactivation ... -
The effect of human mobility and control measures on the COVID-19 epidemic in China
(2020-05-01)The ongoing coronavirus disease 2019 (COVID-19) outbreak expanded rapidly throughout China. Major behavioral, clinical, and state interventions were undertaken to mitigate the epidemic and prevent the persistence of the ... -
Effect of hydroxychloroquine with or without azithromycin on the mortality of coronavirus disease 2019 (COVID-19) patients: a systematic review and meta-analysis
(2020-08-26)Background: Hydroxychloroquine or chloroquine with or without azithromycin have been widely pro-moted to treat coronavirus disease 2019 (COVID-19) following earlyin vitroantiviral effects against se-vere acute respiratory ... -
The Effect of Metformin Consumption on Mortality in Hospitalized COVID-19 patients: a systematic review and meta-analysis
(2020-11-11)Background and aims: Diabetes is one of the most common comorbidities, and it is associated with poorer outcomes in patients with coronavirus disease 2019 (COVID-19). Preliminary findings showed that mortality was reduced ... -
The effect of quercetin on the prevention or treatment of COVID-19 and other respiratory tract infections in humans: A rapid review
(2020-07-30)Brief overview: There is currently insufficient evidence to recommend quercetin supplementation as a therapy for the treatment or prevention of COVID-19. Three human clinical trials with low risk of bias suggest that oral ... -
Effect of remdesivir on patients with COVID-19: A network meta-analysis of randomized control trials
(2020-10-15)Several randomized controlled trials (RCTs) were conducted to investigate the effect of remdesivir for patients with COVID-19, but their results were conflicting. Thus, we conducted a network meta-analysis comparing the ... -
The Effect of Smoking on COVID-19 Symptom Severity: Systematic Review and Meta-Analysis
(2020-09-09)Background: Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SAR2-COV-2) and was first identified in Wuhan, China, in December of 2019, but quickly spread to the rest of the ... -
Effect of the COVID-19 pandemic on mortality of patients with STEMI: a systematic review and meta-analysis
(2020-12-17)[Abstract]. Aims Since the beginning of the SARS-CoV-2 outbreak, hospitals reported declining numbers of patients admitted with ST-segment elevation myocardial infarction (STEMI), indicating that the pandemic might keep ... -
Effectiveness and Safety of Glucocorticoids to Treat COVID-19: A Rapid Review and Meta-Analysis
(2020-04-22)Background: Glucocorticoids are widely used in the treatment of various pulmonary inflammatory diseases, but they are also often accompanied by significant adverse reactions. Published guidelines point out that low dose ... -
Effectiveness and Safety of Short‐stay Units in the Emergency Department: A Systematic Review
(2015-07-22)Objectives: Overcrowding is a serious and ongoing challenge in Canadian hospital emergency departments (EDs) that has been shown to have negative consequences for patient outcomes. The American College of Emergency Physicians ... -
Effectiveness of Intravenous Immunoglobulin for Children with Severe COVID-19: A Rapid Review
(2020-04-22)Background: Intravenous immunoglobulin (IVIG) is usually used as supportive therapy, but the treatment of COVID-19 by IVIG is controversial. This rapid review aims to explore the clinical effectiveness and safety of IVIG ...