Now showing items 1664-1683 of 1749

    • Zika virus and the risk of imported infection in returned travelers: Implications for clinical care 

      Goorhuis, Abraham; von Eije, Karin J; Douma, Renée A; et al. (2016)
      Since late 2015, an unprecedented outbreak of Zika virus is spreading quickly across Southern America. The large size of the current outbreak in The Americas will also result in an increase in Zika virus infections among ...
    • Zika virus associated deaths in Colombia 

      Sarmiento-Ospina, Andrea; Vásquez-Serna, Heriberto; Jimenez-Canizales, Carlos E; et al. (2016-06)
      Zika virus infection has emerged in Latin America as an important threat due to its association with Guillain-Barré syndrome, which can lead to deaths, and microcephaly in newborn babies.1, 2, 3 Cases of fatal Zika virus ...
    • Zika Virus Associated with Meningoencephalitis 

      Carteaux, Guillaume; Maquart, Marianne; Maquart, Marianne; et al. (2016-06)
      Zika virus (ZIKV) is currently spreading widely, while its clinical spectrum remains a matter of investigation. Evidence of a relationship between ZIKV infection and cerebral birth abnormalities is growing. An increased ...
    • Zika Virus Associated with Microcephaly 

      Mlakar, Jernej; Korva, Misa; Tul, Nataša; et al. (2016-06)
      A widespread epidemic of Zika virus (ZIKV) infection was reported in 2015 in South and Central America and the Caribbean. A major concern associated with this infection is the apparent increased incidence of microcephaly ...
    • Zika virus complete genome from Salvador, Bahia, Brazil 

      Giovanetti, Marta; Faria, Nuno Rodrigues; Teixeira, Marcio Roberto; et al. (2016-06)
      In May 2015 the first autochthonous Zika virus infection was reported in Brazil. Rapid and urgent measures are needed to contain the ongoing outbreak. Here we report the full-length ZIKV coding sequence from Bahia. Genetic ...
    • Zika virus damages the human placental barrier and presents marked fetal neurotropism 

      Noronha, Lucia de; Zanluca, Camila; Azevedo, Marina Luize Viola; et al. (2016-06)
      An unusually high incidence of microcephaly in newborns has recently been observed in Brazil. There is a temporal association between the increase in cases of microcephaly and the Zika virus (ZIKV) epidemic. Viral RNA has ...
    • Zika Virus Depletes Neural Progenitors in Human Cerebral Organoids through Activation of the Innate Immune Receptor TLR3 

      Dang, J; Tiwari, SK; Lichinchi, G; et al. (2016-06)
      Emerging evidence from the current outbreak of Zika virus (ZIKV) indicates a strong causal link between Zika and microcephaly. To investigate how ZIKV infection leads to microcephaly, we used human embryonic stem cell-derived ...
    • Zika virus detection in cerebrospinal fluid from two patients with encephalopathy, Martinique, February 2016 

      Rozé, Benoît; Najioullah, Fatiha; Signate, Aïssatou; et al. (2016-06)
      We report two cases of encephalopathy (one with seizures, one with electroencephalogram changes) in patients with Zika virus infection. The cases occurred on Martinique in February 2016, during the Zika virus outbreak. ...
    • Zika virus detection in urine from patients with Guillain-Barre syndrome on Martinique, January 2016 

      Rozé, Benoît; Najioullah, Fatiha; Fergé, Jean-Louis; et al. (2016-06)
      Two cases of Guillain–Barré syndrome (GBS) were diagnosed in January 2016 on Martinique, a French West Indies island of 390,000 inhabitants. Both patients were found to have ZikV in their urine at hospital admission. An ...
    • Zika virus disease epidemic: potential association with microcephaly and Guillain-Barré syndrome 

      Stockholm. European Centre for Disease Prevention and Control (2016-06)
      Main conclusions and options for response Considering the continued rapid spread of Zika virus in the Americas and Caribbean, the growing evidence of an association between Zika virus infection during pregnancy and adverse ...
    • Zika Virus Disease in Colombia — Preliminary Report 

      Pacheco, Oscar; Beltrán, Mauricio; Nelson, Christina A.; et al. (2016-06)
      Background Colombia began official surveillance for Zika virus disease (ZVD) in August 2015. In October 2015, an outbreak of ZVD was declared after laboratory-confirmed disease was identified in nine patients. Methods Using ...
    • Zika Virus Disease in Travelers Returning to the United States, 2010-2014 

      Hennessey, MJ; Fischer, M; Panella, A; et al. (2016-06)
      Zika virus is an emerging mosquito-borne flavivirus that typically causes a mild febrile illness with rash, arthralgia, or conjunctivitis. Zika virus has recently caused large outbreaks of disease in southeast Asia, Pacific ...
    • Zika Virus Disrupts Neural Progenitor Development and Leads to Microcephaly in Mice 

      Li, Cui. et al. (2016-05)
      The link between Zika virus (ZIKV) infection and microcephaly has raised urgent global alarm. The historical African ZIKV MR766 was recently shown to infect cultured human neural precursor cells (NPCs), but unlike the ...
    • Zika Virus Emergence in Mosquitoes in Southeastern Senegal, 2011 

      Diallo, Diawo; Amadou, A.; T. Diagne, Sall Cheikh; et al. (2014)
      Zika virus (ZIKV; genus Flavivirus, family Flaviviridae) is maintained in a zoonotic cycle between arboreal Aedes spp. mosquitoes and nonhuman primates in African and Asian forests. Spillover into humans has been documented ...
    • Zika virus from a Pacific perspective: What are the risks to Australians? 

      A.Taylor, Kathryn; J.Paterson, Beverley (2016-06)
      Zika virus (ZIKV) has risen rapidly from relative obscurity to global attention with the World Health Organization declaring it a Public Health Emergency of International Concern on 1 February 2016 [1]. Much about the virus ...
    • Zika virus genome from the Americas 

      Enfissi, Antoine; Codrington, John; Roosblad, Jimmy; et al. (2016)
      On Oct 1, 2015, a 52-year-old man was hospitalised with exanthema and conjunctivitis at the Academic Hospital in Paramaribo, Suriname. During the next few days, four patients were admitted with mild symptoms including ...
    • Zika virus impairs growth in human neurospheres and brain organoids 

      Garcez, Patricia P.; Loiola, Erick Correia; Costa, Rodrigo Madeiro da; et al. (2016-06)
      The pernicious and resilient Aedes mosquito is rapidly spreading Zika virus (ZIKV) through the Americas. ZIKV infection mostly causes mild disease, but in some patients, nervous system involvement is indicated. A particular ...
    • Zika Virus in a Traveler Returning to China from Caracas, Venezuela, February 2016 

      Li, J; Y, Xiong; W, Wu; et al. (2016-07)
      Zika virus, a member of the Flaviviridae family, is primarily transmitted through Aedes spp. mosquitoes, and evidence of vertical, sexual, and blood transmission of Zika virus has been reported (1–3). The virus has spread ...
    • Zika Virus in an American Recreational Traveler 

      Summers, Dyan J; Wolfe Acosta, Rebecca; Acosta, Alberto M (2016)
      We report the case of a 48-year-old American traveler who presented to our clinic with diffuse rash, malaise, fatigue, fever, arthralgia, low back pain, and bilateral exudative conjunctivitis. The patient had an extensive ...
    • Zika virus in Brazil and macular atrophy in a child with microcephaly 

      Ventura, Camila V; Maia, Mauricio; Bravo-Filho, Vasco; et al. (2016)
      Zika virus (ZIKV), a mosquito-borne Flavivirus, was first reported in human beings in 1952.1 Before April, 2015, no case had been reported in Brazil. However, between April and November, 2015, 18 of the 27 Brazilian states ...