Browsing Technical documents and research evidence on COVID-19 by Title
Now showing items 1399-1418 of 1749
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The SARS-CoV-2 Vaccine Pipeline: an Overview
(2020-03-03)Purpose of Review: The goal of this review is to provide a timely overview on efforts to develop a vaccine for the 2019 novel coronavirus SARS-CoV-2, the causative agent of coronavirus disease (COVID-19). Recent Findings: ... -
SARS-CoV-2 viral load and the severity of COVID-19
(2020-03-26)The initial dose of virus and the amount of virus an individual has at any one time might worsen the severity of COVID 19 disease. Viral load is a measure of the number of viral particles present in an individual. Higher ... -
SARS-CoV-2: a storm is raging
(2020-03-27)The pandemic coronavirus infectious disease (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is rapidly spreading across the globe. In this issue of the JCI, Chen and colleagues compared ... -
A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection
(2016-07)Currently there are no approved vaccines or specific therapies to prevent or treat Zika virus (ZIKV) infection. We interrogated a library of FDA-approved drugs for their ability to block infection of human HuH-7 cells by ... -
Screening for SARS-CoV-2 infections with colorimetric RT-LAMP and LAMP sequencing
(2020-05-09)The SARS-CoV-2 (COVID-19) pandemic poses a significant public-health problem. In order to control the pandemic, rapid tests for detecting existing infections and assessing virus spread are critical. Approaches to detect ... -
Screening of Blood Donations for Zika Virus Infection - Puerto Rico, April 3-June 11, 2016
(2016-06)Transfusion-transmitted infections have been documented for several arboviruses, including West Nile and dengue viruses (1). Zika virus, a flavivirus transmitted primarily by Aedes aegypti mosquitoes that has been identified ... -
Semi-recumbent position reduces the risk of clinically suspected VAP in patients on mechanical ventilation, compared to a supine position
(2020-03-24)Citation: Wang L, Li X, Yang Z, et al. Semi-recumbent position versus supine position for the prevention of ventilator-associated pneumonia in adults requiring mechanical ventilation. Cochrane Database of Systematic Reviews ... -
Sensitivity and specificity of a rapid test for assessment of exposure to SARS-CoV-2 in a community-based setting in Brazil
(2020-05-10)Background: While the recommended laboratory diagnosis of COVID-19 is a molecular based assay, population-based studies to determine the prevalence of COVID-19 usually use serological assays. Objective: To evaluate the ... -
Sensitivity assessment of SARS-CoV-2 PCR assays developed by WHO referral laboratories
(2020-05-04)The sensitivity of SARS-CoV-2 RT-PCR tests developed by Charite (Germany), HKU (Hong-Kong), China CDC (China), US CDC (United-States), and Institut Pasteur, Paris (France) was assessed on SARS-CoV-2 cell culture supernatants ... -
Sensitivity of Nasopharyngeal, Nasal and Throat Swab for the Detection of SARS-CoV-2
(2020-05-08)Nasopharyngeal (NP), nasal and throat swabs are the most practical specimen sources to test for upper respiratory pathogens. We compared the sensitivity of NP, nasal and throat swabs to detect SARS-CoV-2 in community ... -
A sero-epidemiological survey for certain arboviruses (Togaviridae) in Pakistan
(2014)Complement-fixation test reactions to eight viruses of the family Togaviridae were studied in 372 serum samples (157 rodents, 172 domestic animals, 43 humans) from Pakistan. Antibodies to each tested virus were detected. ... -
Serologic responses to SARS-CoV-2 infection among hospital staff with mild disease in eastern France
(2020-05-22)Background: The serologic response of individuals with mild forms of SARS-CoV-2 infection is poorly characterized. Methods: Hospital staff who had recovered from mild forms of PCR-confirmed SARS-CoV-2 infection were tested ... -
Serological and entomological study on yellow fever in Sierra Leone
(2014)In a serological and entomological survey on yellow fever carried out in Sierra-Leone in 1972, altogether 899 sera from children 0 to 14 years were tested with 12 antigens by haemagglutination-inhibition and complement ... -
Serological assays for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), March 2020
(2020-04-14)Background: The ongoing coronavirus disease (COVID-19) pandemic has major impacts on health systems, the economy and society. Assessing infection attack rates in the population is critical for estimating disease severity ... -
Serological immunochromatographic approach in diagnosis with SARS-CoV-2 infected COVID-19 patients
(2020-03-26)An outbreak of new coronavirus SARS-CoV-2 was occurred in Wuhan, China and rapidly spread to other cities and nations. The standard diagnostic approach that widely adopted in the clinic is nucleic acid detection by real-time ... -
Serological survey for arbovirus antibodies in the human and simian populations of the South-East of Gabon (author's transl)
(2014)A serological survey for arbovirus antibodies was carried out in human and simian populations of the South-East of Gabon. 197 human sera (adults), 34 simian sera (collected in the monkey colony of the Centre International ... -
Serological survey for the prevalence of certain arboviruses in the human population of the south-east area of Central African Republic (author's transl)
(2014)A serological survey of antibodies to arboviruses was carried out in the human population of the south-east part of Central African Republic in April 1979. Four hundred and fifty nine serum samples were tested using the ... -
A serological survey of arboviruses in Gabon
(2014)Serological studies for arbovirus antibodies were carried out on 1.279 human serum specimens collected from adults in south-eastern part of Gabon from June to September 1975 during a multipurpose epidemiological survey. ...