Browsing Technical documents and research evidence on COVID-19 by Title
Now showing items 107-126 of 1749
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BMJ Best Practice: Management of coexisting conditions in the context of COVID-19. Straight to the point of care
(2020-09-30)This page summarises important considerations for the care of people with co-existing medical conditions during the COVID-19 pandemic. Key points from guidance and position statements are summarised for each condition, and ... -
Bounding the Predictive Values of COVID-19 Antibody Tests
(2020-05-17)COVID-19 antibody tests have imperfect accuracy. There has been lack of clarity on the meaning of reported rates of false positives and false negatives. For risk assessment and clinical decision making, the rates of interest ... -
Breakthrough: Chloroquine Phosphate Has Shown Apparent Efficacy in Treatment of COVID-19 Associated Pneumonia in Clinical Studies
(2020-02-29)The coronavirus disease 2019 (COVID-19) virus is spreading rapidly, and scientists are endeavoring to discover drugs for its efficacious treatment in China. Chloroquine phosphate, an old drug for treatment of malaria, is ... -
Breastfeeding and Coronavirus Disease‐2019. Ad interim indications of the Italian Society of Neonatology endorsed by the Union of European Neonatal & Perinatal Societies
(2020-04-03)[Abstract]. The recent COVID‐19 pandemic has spread to Italy with heavy consequences on public health and economics. Besides the possible consequences of COVID‐19 infection on a pregnant woman and the fetus, a major concern ... -
Breastfeeding of Infants Born to Mothers with COVID-19: A Rapid Review
(2020-04-19)Abstract Background: Existing recommendations on whether mothers with COVID-19 should continue breastfeeding are still conflicting. We aimed to conduct a rapid review of mother-to-child transmission of COVID-19 during ... -
Buffered solutions did not reduce mortality compared to 0.9% saline for resuscitation in critically ill adults and children
(2020-03-22)What is this? Some patients with COVID-19 will become critically ill and need intravenous fluids. Saline 0.9% is the most commonly used crystalloid solutions for critically ill patients, but buffered solutions are also ... -
Can Chinese Medicine Be Used for Prevention of Corona Virus Disease 2019 (COVID-19)?: A Review of Historical Classics, Research Evidence and Current Prevention Programs
(2020-02)[Objective] Since December 2019, an outbreak of corona virus disease 2019 (COVID-19) occurred in Wuhan, and rapidly spread to almost all parts of China. This was followed by prevention programs recommending Chinese medicine ... -
Can early and high intravenous dose of vitamin C prevent and treat coronavirus disease 2019 (COVID-19)?
(2020-03-26)Because the development of efficacious vaccines and antiviral drugstakes time, vitamin C and other antioxidants are among currently available agentsto mitigate COVID-19 associated ARDS. Given the fact that high-dose VC ... -
Can Nebulised Heparin Reduce Time to Extubation in SARS CoV 2 The CHARTER Study Protocol
(2020-05-12)Introduction: COVID 19 is associated with the development of ARDS displaying the typical features of diffuse alveolar damage with extensive pulmonary coagulation activation resulting in fibrin deposition in the microvasculature ... -
Can symptoms of anosmia and dysgeusia be diagnostic for COVID‐19?
(2020-11-20)Objective: Olfactory and taste dysfunction (OTD) is a potential neurological manifestation of coronavirus-2019 (COVID-19). We aimed to investigate the diagnostic value of symptoms of anosmia and dysgeusia for COVID-19. Methods: ... -
Can symptoms of anosmia and dysgeusia be diagnostic for COVID‐19?
(2020-11)Objective: Olfactory and taste dysfunction (OTD) is a potential neurological manifestation of coronavirus-2019 (COVID-19). We aimed to investigate the diagnostic value of symptoms of anosmia and dysgeusia for COVID-19. Methods: ... -
Can the Coronavirus Disease 2019 (COVID-19) Affect the Eyes? A Review of Coronaviruses and Ocular Implications in Humans and Animals
(2020-03-16)In December 2019, a novel coronavirus (CoV) epidemic, caused by the severe acute respiratory syndrome coronavirus - 2 (SARS-CoV-2) emerged from China. This virus causes the coronavirus disease 2019 (COVID-19). Since then, ... -
Can we distinguish respiratory viral infections based on clinical features? A prospective pediatric cohort compared to systematic literature review
(2018-07-24)Studies have shown that the predictive value of “clinical diagnoses” of influenza and other respiratory viral infections is low, especially in children. In routine care, pediatricians often resort to clinical diagnoses, ... -
Can we use these masks? Rapid Assessment of the Inhalation Resistance Performance of Uncertified Medical Face Masks in the Context of Restricted Resources Imposed during a Public Health Emergency
(2020-05-19)In the case of a public health emergency such as the COVID-19 pandemic, access to large quantities of appropriate personal protection equipment (PPE) has presented a significant problem. A shortage of face masks and ... -
Cancer is associated with the severity and mortality of patients with COVID-19: a systematic review and meta-analysis
(2020-05-06)Background: Cancer patients are considered a highly vulnerable population in the COVID-19 epidemic, but the relationship between cancer and the severity and mortality of patients with COVID-19 remains unclear. This study ... -
Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19)
(2020-03-27)Importance: Virus infection has been widely described as one of the most common causes of myocarditis. However, less is known about the cardiac involvement as a complication of severe acute respiratory syndrome coronavirus ... -
Cardiac safety of off-label COVID-19 drug therapy: a review and proposed monitoring protocol
(2020-05-06)More than 2,000,000 individuals worldwide have had coronavirus 2019 disease infection (COVID-19), yet there is no effective medical therapy. Multiple off-label and investigational drugs, such as chloroquine and hydroxychloroquine, ... -
The Cardiac Toxicity of Chloroquine or Hydroxychloroquine in COVID-19 Patients: A Systematic Review and Meta-regression Analysis
(2020-10-19)Objective: To systematically review the literature and estimate the risk of Chloroquine (CQ) and hydroxychloroquine (HCQ) cardiac toxicity in COVID-19 patients. Methods: We searched multiple data sources including ... -
Cardio-Cerebrovascular Disease is Associated With Severity and Mortality of COVID-19: A Systematic Review and Meta-Analysis
(2020-08-27)At present, COVID-19 is raging all over the world. Many comorbidities, such as diabetes mellitus (OR = 2.67, 95% CI = 1.91–3.74) and hypertension (OR = 2.3, 95% CI = 1.76–3.00), have been shown to worsen the patient’s ... -
Cardiovascular Collapse in COVID-19 Infection: The Role of Veno-Arterial Extracorporeal Membrane Oxygenation (VA-ECMO)
(2020-04-04)COVID-19 has been associated with cardiovascular complications including acute cardiac injury, heart failure and cardiogenic shock. The role of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) in the event of ...