Browsing Technical documents and research evidence on COVID-19 by Title
Now showing items 1054-1073 of 1749
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Noninvasive positive-pressure ventilation may help wean patients off mechanical ventilation
(2020-03-20)What is this? Some patients with COVID-19 will develop respiratory failure and need help with their breathing. This might be provided by mechanical ventilation (MV) in an intensive care unit (ICU), but this can cause ... -
Nonsurgical management of resectable oral cavity cancer in the wake of COVID-19: A rapid review and meta-analysis
(2020-06-10)Objective: Surgery is the preferred treatment modality for oral squamous cell carcinoma (OSCC). However, due to limited resources, re-assessment of treatment paradigms in the wake of the Coronavirus Disease 2019 (COVID-19) ... -
Notes from the Field: Evidence of Zika Virus Infection in Brain and Placental Tissues from Two Congenitally Infected Newborns and Two Fetal Losses - Brazil, 2015
(2016-06)Zika virus is a mosquito-borne flavivirus that is related to dengue virus and transmitted primarily by Aedes aegypti mosquitoes, with humans acting as the principal amplifying host during outbreaks. Zika virus was first ... -
Novel Approach to Reduce Transmission of COVID-19 During Tracheostomy
(2020-04-06)Severe infection involving the novel coronavirus 2019 (COVID-19) has been associated with acute respiratory distress syndrome that subsequently requires patients to be intubated and dependent on mechanical ventilation. In ... -
The Novel Coronavirus Disease (COVID-19): A PRISMA Systematic Review and Meta-analysis of Clinical and Paraclinical characteristics
(2020-04-22)An outbreak of pneumonia, caused by a novel coronavirus (COVID-19) was Identified in China in Dec 2019. This virus expanded worldwide, causing global concern. Clinical, laboratory and imaging features of this infection are ... -
Novel Coronavirus Infection (COVID-19) in Humans: A Scoping Review and Meta-Analysis
(2020-03-30)A growing body of literature on the 2019 novel coronavirus (SARS-CoV-2) is becoming available, but a synthesis of available data has not been conducted. We performed a scoping review of currently available clinical, ... -
Novel Coronavirus(2019-nCoV). Situation Report – 22, Data as reported by 11 February 2020
(2020-02-11)HIGHLIGHTS: • No new countries reported cases of 2019-nCoV in the past 24 hours. • An advanced team is currently in Beijing to prepare an international mission and to determine the questions the international team will ... -
A novel strategy for community screening of SARS-CoV-2 (COVID-19): Sample pooling method
(2020-08-28)The rapid global spread of the coronavirus disease (COVID-19) has inflicted significant health and socioeconomic burden on affected countries. As positive cases continued to rise in Malaysia, public health laboratories ... -
NSAIDs for analgesia in the era of COVID-19
(2020-06-03)Globally, non-steroidal anti-inflammatory drugs (NSAIDs) are highly used to treat pain. With the rise of the COVID-19 pandemic, the safety of NSAIDs use has been called into question. These concerns are worthy of review. ... -
Nucleoside inhibitors of Zika virus
(2016)There is growing evidence that Zika virus (ZIKV) can cause devastating infant brain defects and other neurological disorders in humans. However, no specific antiviral therapy is available at present. We tested a series of ... -
Nurse-initiated medications in the emergency department
(2020-05-13)What is this? The COVID-19 pandemic is placing a strain on healthcare services and resources. Existing research on expanding healthcare professionals’ roles, such as prescribing by nurses, may provide useful information ... -
Obesity a predictor of outcomes of COVID‐19 hospitalized patients‐ A systematic Review and Meta‐Analysis
(2020-09-25)Background: COVID‐19 pandemic is a global health crisis. Very few studies have reported association between obesity and severity of COVID‐19. In this meta‐analysis, we assessed the association of obesity and outcomes in ... -
Obesity Increases the Severity and Mortality of Influenza and COVID-19: A Systematic Review and Meta-Analysis
(2020-12-21)Since December 2019, COVID-19 has aroused global attention. Studies show the link between obesity and severe outcome of influenza and COVID-19. Thus, we aimed to compare the impacts of obesity on the severity and mortality ... -
Objectives for COVID-19 testing in school settings – first update
(2020-08-21)This document provides an overview of major aspects of testing, contact tracing, contact identification and contact follow-up in school settings within the EU/EEA countries and the United Kingdom (UK). -
Occurrence and Timing of Subsequent SARS-CoV-2 RT-PCR Positivity Among Initially Negative Patients
(2020-05-08)Background: SARS-CoV-2 reverse transcriptase polymerase chain reaction (RT-PCR) testing remains the cornerstone of laboratory-based identification of patients with COVID-19. As the availability and speed of SARS-CoV-2 ... -
Occurrence and transmission potential of asymptomatic and presymptomatic SARS-CoV-2 infections: A living systematic review and meta-analysis
(2020-09-22)Background: There is disagreement about the level of asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. We conducted a living systematic review and meta-analysis to address three questions: ... -
Ocular Findings in Infants With Microcephaly Associated With Presumed Zika Virus Congenital Infection in Salvador, Brazil
(2016-06)IMPORTANCE: The Zika virus (ZIKV) has rapidly reached epidemic proportions, especially in northeastern Brazil, and has rapidly spread to other parts of the Americas. A recent increase in the prevalence of microcephaly in ... -
Of Chloroquine and COVID-19
Recent publications have brought attention to the possible benefit of chloroquine, a broadly used antimalarial drug, in the treatment of patients infected by the novel emerged coronavirus (SARS-CoV-2). The scientific ... -
Off-Label Real World Experience Using Tocilizumab for Patients Hospitalized with COVID-19 Disease in a Regional Community Health System: A Case-Control Study
(2020-05-19)Objective: To determine if Tocilizumab treatment in patients hospitalized with laboratory confirmed SARS-CoV-2 infection and subsequent COVID-19 disease provides short-term survival benefit. Design: Case-control, observational ... -
Off-label use of medicines for COVID-19. Scientific brief, 31 March 2020
(2020-03-31)No pharmaceutical products have yet been shown to be safe and effective for the treatment of COVID-19. However, a number of medicines have been suggested as potential investigational therapies, many of which are now being ...