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dc.contributor.authorSaad, Mariam Ahmed et al.
dc.date.accessioned2021-01-20T15:56:37Z
dc.date.available2021-01-20T15:56:37Z
dc.date.issued2020-10-29
dc.identifier.urihttps://doi.org/10.2174/1573397116666201029155856en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12663/2487
dc.description.abstractIntroduction: Over 4.9 million cases of Coronavirus disease 2019 (COVID-19) have been confirmed since the worldwide pandemic began. Since the emergence of COVID-19, a number of confirmed cases reported autoimmune manifestations. Herein, we reviewed the reported COVID-19 cases with associated autoimmune manifestations. Methods: We searched PubMed database using all available keyword for COVID-19. All related studies between January 1st, 2020 to May 22nd, 2020 were reviewed. Only studies published in English language were considered. Articles were screened based on titles and abstract. All reports of confirmed COVID-19 patients who have associated clinical evidence of autoimmune disease were selected. Results: Among 10006 articles, searches yielded, Thirty-two relevant articles for full-text assessment. Twenty studies meet the eligibility criteria. The twenty eligible articles reported 33 cases of confirmed COVID-19 diagnosis who developed an autoimmune disease after the onset of covid-19 symptoms. Ages of patients varied from a 6 months old infant to 89 years old female (Mean=53.9 years of 28 cases); five cases had no information regarding their age. The time between symptoms of viral illness and onset of autoimmune symptoms ranged from 2 days to 33 days (Mean of the 33 cases=9.8 days). Autoimmune diseases were one case of subacute thyroiditis (3%), two cases of Kawasaki Disease (6.1%), three cases of coagulopathy and antiphospholipid syndrome (9.1%), three cases of immune thrombocytopenic purpura (9.1%), eight cases of autoimmune hemolytic anemia (24.2%), and sixteen cases of Guillain–Barré syndrome (48.5%). Conclusions: COVID-19 has been implicated in the development in a range of autoimmune diseases which may shed a light on the association between autoimmune diseases and infections. Purchase is needed to have access to the full version of this article.en_US
dc.languageEnglishen_US
dc.subjectCOVID-19en_US
dc.subjectCoronavirusen_US
dc.subjectCoronavirus Infectionsen_US
dc.subjectInfectious Diseasesen_US
dc.subjectBetacoronavirusen_US
dc.subjectAntiphospholipid Syndromeen_US
dc.subjectAutoimmune Diseasesen_US
dc.subjectGuillain-Barre Syndromeen_US
dc.subjectPurpura, Thrombocytopenic, Idiopathicen_US
dc.subjectMucocutaneous Lymph Node Syndromeen_US
dc.subjectSARS-CoV-2en_US
dc.titleCOVID-19 and Autoimmune Diseases: A Systematic Review of Reported Casesen_US
eihealth.countryOthersen_US
eihealth.categoryClinical characterization and managementen_US
eihealth.typePublished Articleen_US
eihealth.maincategorySave Lives / Salvar Vidasen_US
dc.relation.ispartofjournalCurrent Rheumatology Reviewsen_US


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