dc.contributor.author | Lam, Tommy Tsan-Yuk et al. | |
dc.date.accessioned | 2020-12-30T20:04:08Z | |
dc.date.available | 2020-12-30T20:04:08Z | |
dc.date.issued | 2020-03-26 | |
dc.identifier.uri | https://doi.org/10.1038/s41586-020-2169-0 | en_US |
dc.identifier.uri | https://hdl.handle.net/20.500.12663/2448 | |
dc.description.abstract | The ongoing outbreak of viral pneumonia in China and across the world is associated with a new coronavirus, SARS-CoV-2. This outbreak has been tentatively associated with a seafood market in Wuhan, China, where the sale of wild animals may be the source of zoonotic infection. Although bats are probable reservoir hosts for SARS-CoV-2, the identity of any intermediate host that may have facilitated transfer to humans is unknown. Here we report the identification of SARS-CoV-2-related coronaviruses in Malayan pangolins (Manis javanica) seized in anti-smuggling operations in southern China. Metagenomic sequencing identified pangolin-associated coronaviruses that belong to two sub-lineages of SARS-CoV-2-related coronaviruses, including one that exhibits strong similarity in the receptor-binding domain to SARS-CoV-2. The discovery of multiple lineages of pangolin coronavirus and their similarity to SARS-CoV-2 suggests that pangolins should be considered as possible hosts in the emergence of new coronaviruses and should be removed from wet markets to prevent zoonotic transmission. | en_US |
dc.language | English | en_US |
dc.subject | COVID-19 | en_US |
dc.subject | Coronavirus Infections | en_US |
dc.subject | Coronavirus | en_US |
dc.subject | Infectious Diseases | en_US |
dc.subject | Virus Diseases | en_US |
dc.subject | SARS-CoV-2 | en_US |
dc.subject | Betacoronavirus | en_US |
dc.title | Identifying SARS-CoV-2-related coronaviruses in Malayan pangolins | en_US |
eihealth.country | Global (WHO/OMS) | en_US |
eihealth.category | Virus: natural history, transmission and diagnostics | en_US |
eihealth.type | Published Article | en_US |
eihealth.maincategory | Slow Spread / Reducir la Dispersión | en_US |
dc.relation.ispartofjournal | Nature | en_US |