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dc.contributor.authorZhang, Cantong et al.
dc.date.accessioned2020-12-22T19:44:55Z
dc.date.available2020-12-22T19:44:55Z
dc.date.issued2020-03-26
dc.identifier.urihttps://doi.org/10.1002/jmv.25788en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12663/2438
dc.description.abstractAn outbreak of severe acute respiratory syndrome‐related coronavirus 2 infection has posed significant threats to international health and the economy. In the absence of specific treatment for this virus, there is an urgent need to learn from the experience and lessons in China. To reduce the case‐fatality rate among coronavirus disease 2019 patients, we should not ignore the complications, such as RNAaemia, acute respiratory distress syndrome, and multiple organ dysfunction. To help understand the advantages and limitations of differential treatments, we provide a timely review and discuss the complications and corresponding major treatments, especially controversial ones such as antiviral therapy (remdesivir, ribavirin, and chloroquine), glucocorticoid therapy, extracorporeal support including an artificial liver system, and extracorporeal membrane oxygenation based on available evidence. As a result, we suggest that antiviral therapy and organ function support are vital to reduce mortality for mild patients and critical patients, respectively.en_US
dc.languageEnglishen_US
dc.subjectCOVID-19en_US
dc.subjectCoronavirusen_US
dc.subjectCoronavirus Infectionsen_US
dc.subjectInfectious Diseasesen_US
dc.subjectReviewen_US
dc.subjectSARS‐CoV‐2en_US
dc.subjectPneumoniaen_US
dc.subjectTherapeuticsen_US
dc.titleControversial treatments: An updated understanding of the coronavirus disease 2019en_US
eihealth.countryOthersen_US
eihealth.categoryCandidate therapeutics RDen_US
eihealth.typePublished Articleen_US
eihealth.maincategorySave Lives / Salvar Vidasen_US
dc.relation.ispartofjournalJournal of Medical Virologyen_US


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