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dc.contributor.authorJuly, Julius
dc.contributor.authorPranata, Raymond
dc.date.accessioned2020-09-23T18:37:33Z
dc.date.available2020-09-23T18:37:33Z
dc.date.issued2020-07-22
dc.identifier.urihttps://doi.org/10.1016/j.jstrokecerebrovasdis.2020.105185en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12663/2260
dc.description.abstractBackground: This systematic review and meta-analysis aimed to evaluate the impact of the coronavirus disease (COVID-19) pandemic on stroke care, including the number of stroke alerts/codes, number of reperfusions, and number of thrombectomies during the pandemic compared to those during the pre-pandemic period. Methods: A systematic literature search was performed using the PubMed, EuropePMC, and Cochrane Central databases. The data of interest were the number of strokes, reperfusions, and mechanical thrombectomies during the COVID-19 pandemic versus that during the pre-pandemic period (in a historical comparator group over a specified period of same period length). Results: The study included 59,233 subjects from 9 studies. Meta-analysis showed that the number of stroke alerts during the pandemic was 64% (56–71%) of that during the pre-pandemic period. The number of reperfusion therapies during the pandemic was 69% (61–77%) of that during the pre-pandemic period. Pooled analysis showed that the number of mechanical thrombectomies performed during the pandemic was 78% (75–80%) of that during the pre-pandemic period. The number of mechanical thrombectomies per stroke patient was higher during the pandemic (OR 1.23 [1.12–1.36], p < 0.001; I2: 0%, p = 0.845). Conclusion: This meta-analysis showed that the number of stroke alerts, reperfusions, and mechanical thrombectomies was reduced by 36%, 31%, and 22%, respectively, during the pandemic. However, the number of patients receiving mechanical thrombectomy per stroke increased.en_US
dc.languageEnglishen_US
dc.subjectCOVID-19en_US
dc.subjectCerebrovascular Disordersen_US
dc.subjectSARS-CoV-2en_US
dc.subjectStrokeen_US
dc.subjectThrombectomyen_US
dc.subjectSystematic Reviewen_US
dc.subjectMeta-Analysisen_US
dc.subjectCoronavirus Infectionsen_US
dc.titleImpact of the Coronavirus Disease Pandemic on the Number of Strokes and Mechanical Thrombectomies: A Systematic Review and Meta-Analysisen_US
eihealth.countryOthersen_US
eihealth.categoryHealth systems and servicesen_US
eihealth.typePublished Articleen_US
eihealth.maincategorySave Lives / Salvar Vidasen_US
dc.relation.ispartofjournalJ Stroke Cerebrovasc Disen_US


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