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Envíos recientes
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Zika Virus in a Traveler Returning to China from Caracas, Venezuela, February 2016
(2016-07)Zika virus, a member of the Flaviviridae family, is primarily transmitted through Aedes spp. mosquitoes, and evidence of vertical, sexual, and blood transmission of Zika virus has been reported (1–3). The virus has spread ... -
Microcephaly in Infants, Pernambuco State, Brazil, 2015
(2016-07)We studied the clinical characteristics for 104 infants born with microcephaly in the delivery hospitals of Pernambuco State, Brazil, during 2015. Testing is ongoing to exclude known infectious causes. However, microcephaly ... -
Mucocutaneous Findings and Course in an Adult With Zika Virus Infection
(2016-07)Importance The Zika virus epidemic has been declared a public health emergency of international concern by the World Health Organization. We describe the mucocutaneous features and histologic correlation in a patient with ... -
Highly diversified Zika viruses imported to China, 2016
(2016-07)First discovered during 1947 in Uganda from febrile rhesus macaques, Zika virus (ZIKV) is a mosquito-borne, re-emerging flavivirus historically known to be present in much of Africa and Asia, occasionally causing outbreaks ... -
An Infectious cDNA Clone of Zika Virus to Study Viral Virulence, Mosquito Transmission, and Antiviral Inhibitors
(2016-07)The Asian lineage of Zika virus (ZIKV) has recently caused epidemics and severe disease. Unraveling the mechanisms causing increased viral transmissibility and disease severity requires experimental systems. We report an ... -
Model-based projections of Zika virus infections in childbearing women in the Americas
(2016-07)Zika virus is a mosquito-borne pathogen that is rapidly spreading across the Americas. Due to associations between Zika virus infection and a range of fetal maladies(1,2), the epidemic trajectory of this viral infection ... -
Zika virus infection in pregnant women in Honduras
(2016-07)Background: Although there is increasing evidence for a relationship between symptomatic Zika virus (ZIKV) maternal infection, and microcephaly, a firm causal relation has yet to be established by epidemiologic studies. ... -
Neurologic manifestations of arboviruses in the epidemy of pernambuco, Brazil
(2016-07)INTRODUCTION Dengue has affected Rio de Janeiro City since the 1980s. The sequential Zika and chikungunya virus introductions during 2015 aggravated the health scenario, with 97,241 cases of arboviral diseases reported ... -
Safety and Immunogenicity of a Zika Virus DNA Vaccine, VRC-ZKADNA085-00-VP, in Healthy Adults
(2016-07)The Zika virus is passed to humans by infected mosquitos. It usually causes fever, rash, joint pain, and red eyes. Recently, some cases of microcephaly (abnormally small head) were reported in babies born to mothers infected ... -
Acute Zika infection with concurrent onset of Guillain-Barré Syndrome
(2016-07)A 47-year-old Tongan male returning to New Zealand after a 2-week holiday in Tonga presented with 3 days of progressive limb weakness, numbness, unsteady gait, and dyspnea. Two days before departing Tonga (6 days before ... -
A Screen of FDA-Approved Drugs for Inhibitors of Zika Virus Infection
(2016-07)Currently there are no approved vaccines or specific therapies to prevent or treat Zika virus (ZIKV) infection. We interrogated a library of FDA-approved drugs for their ability to block infection of human HuH-7 cells by ... -
The Evaluation of Potential Zika, Chikungunya, and Dengue Infections in Mexico (Zik01)
(2016-07)The proportion of subjects that have confirmed Zika, Chikungunya, or Dengue (including co-infections) from the subjects presenting with fever and/or rash in southeastern Mexico. -
Zika virus infection in pregnant women in Honduras
(2016-07)Background: Although there is increasing evidence for a relationship between symptomatic Zika virus (ZIKV) maternal infection, and microcephaly, a firm causal relation has yet to be established by epidemiologic studies. ... -
A robust method for the rapid generation of recombinant Zika virus expressing the GFP reporter gene
(2016-07)Zika virus (ZIKV) infection is a major public health problem with severe human congenital and neurological anomalies. The screening of anti-ZIKV compounds and neutralizing antibodies needs reliable and rapid virus-based ... -
Zika virus-associated Guillain-Barre syndrome variant in Haiti
(2016-05)Zika virus is a single-stranded RNA virus (genus Flavivirus) transmitted by the Aedes mosquito and through sexual contact with infected individuals.1,2 Zika virus infection may be asymptomatic or may cause fever, rash, ... -
Zika Virus Infects Human Placental Macrophages
(2016-07)The recent Zika virus (ZIKV) outbreak in Brazil has been directly linked to increased cases of microcephaly in newborns. Current evidence indicates that ZIKV is transmitted vertically from mother to fetus. However, the ... -
Zika Virus Disrupts Neural Progenitor Development and Leads to Microcephaly in Mice
(2016-05)The link between Zika virus (ZIKV) infection and microcephaly has raised urgent global alarm. The historical African ZIKV MR766 was recently shown to infect cultured human neural precursor cells (NPCs), but unlike the ... -
Single-Reaction Multiplex Reverse Transcription PCR for Detection of Zika, Chikungunya, and Dengue Viruses
(2016-07)Clinical manifestations of Zika virus, chikungunya virus, and dengue virus infections can be similar. To improve virus detection, streamline molecular workflow, and decrease test costs, we developed and evaluated a multiplex ... -
Mapping Zika in municipalities of one coastal department of Colombia (Sucre) using geographic information systems during the 2015-2016 outbreak: implications for public health and travel advice
(2016-05)Zika virus (ZIKV) infection emerged in 2015 as one of the most significant tropical infectious diseases in Latin America, following the geographical distribution of chikungunya virus (CHIKV). These viruses share high ... -
Zika Virus-Related News Coverage and Online Behavior, United States, Guatemala, and Brazil
(2016-07)News coverage of emerging infectious diseases tends to be episodic and ephemeral rather than thematic, comprehensive, and consistent over time, in part because of newsroom constraints (1–3). Public health authority ...