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NICE, RCGP and SIGN publish guideline on managing the long-term effects of COVID-19
(2020-12-18)The guideline covers the care of people who have signs and symptoms that develop during or after an infection consistent with COVID-19, that continue for more than 4 weeks and are not explained by an alternative diagnosis. ... -
Covid-19 update: ADHD, renal transplant patients, care for covid-19 patients post discharge
(2020-07-02)Kieran Walsh, clinical director at BMJ, asks editors from BMJ Learning and BMJ Best Practice to summarise the latest clinical guidance related to covid-19. Abigail Davis discusses the latest guidance on ADHD and renal ... -
Covid-19 and comorbidities
(2020-12-03)A recent meta-analysis by Espinosa and colleagues, “Prevalence of Comorbidities in Patients and Mortality Cases Affected by SARS-CoV2”, found that 42% of patients with Covid-19 had comorbidities. Furthermore, 61% of those ... -
Mental health impacts of the COVID-19 pandemic (multiple reviews)
(2021-02-22)What is this? The COVID-19 pandemic is placing a psychological and psychosocial burden on patients and wider society. Several reviews of the mental health impacts of COVID-19 and other pandemics are summarised here. More ... -
The prevalence of psychological consequences of COVID-19: A systematic review and meta-analysis of observational studies
(2020-10-29)A systematic review and a meta-analysis were conducted to examine the overall prevalence of psychological health outcomes during COVID-19. Seven databases were systematically searched to include studies reporting on at ... -
The Prevalence of Gastrointestinal Symptoms, Abnormal Liver Function, Digestive System Disease and Liver Disease in COVID-19 Infection A Systematic Review and Meta-Analysis
(2020-10-27)Background: The worldwide outbreak of COVID-19 infected millions of people. Some patients had gastrointestinal (GI) symptoms, abnormal liver function, digestive system disease and liver disease. Aim: To investigate the ... -
More than Pneumonia: Distinctive Features of SARS-Cov-2 Infection. From Autopsy Findings to Clinical Implications: A Systematic Review
(2020-10-23)Despite safety recommendations for the management of corpses with COVID-19 infection and the high number of deaths worldwide, the post-mortem investigation rate is extremely low as well as the scientific contributions ... -
The Impact of COVID-19 on Blood Glucose: A Systematic Review and Meta-Analysis
(2020-10-05)Background: Diabetes mellitus is considered a common comorbidity of COVID-19, which has a wide spectrum of clinical manifestations ranging from asymptomatic infection to severe respiratory symptoms and even death. However, ... -
Stroke and Novel Coronavirus Infection in Humans: A Systematic Review and Meta-Analysis
(2020-10-06)Background: As the world witnessed the devastation caused by the coronavirus disease 2019 (COVID-19) outbreak, a growing body of literature on COVID-19 is also becoming increasingly available. Stroke has increasingly been ... -
Remdesivir: A potential game-changer or just a myth? A systematic review and meta-analysis
(2020-10-26)Aims: COVID-19 outbreak has created a public health catastrophe all over the world. Here, we have aimed to conduct a systematic review and meta-analysis on remdesivir use for COVID-19. Main methods: We searched Pubmed, ... -
Incidence of Myocardial Injury in COVID-19-Infected Patients: A Systematic Review and Meta-Analysis
(2020)Introduction: The incidence of acute myocardial injury (AMI) among Coronavirus Disease 19 (COVID-19)-infected patients remain unclear. We aimed to conduct a systematic review and meta-analysis to further explore the incidence ... -
Efficacy of Lopinavir/Ritonavir Compared With Standard Care for Treatment of Coronavirus Disease 2019 (COVID-19): A Systematic Review
(2020-10-29)Background: Coronavirus disease 2019 (COVID-19) is a newly discovered multi-organ disease caused by the novel coronavirus SARS-CoV-2. Currently, there are no official guidelines on the pharmacological treatment of COVID-19. ... -
Efficacy and safety of remdesivir in hospitalized Covid‐19 patients: Systematic review and meta‐analysis including network meta‐analysis
(2020-10-31)Remdesivir is an antiviral agent that has shown broad‐spectrum activity, including against severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Clinical trials investigating the role of remdesivir in coronavirus ... -
COVID-19 and Autoimmune Diseases: A Systematic Review of Reported Cases
(2020-10-29)Introduction: Over 4.9 million cases of Coronavirus disease 2019 (COVID-19) have been confirmed since the worldwide pandemic began. Since the emergence of COVID-19, a number of confirmed cases reported autoimmune manifestations. ... -
Addition of Tocilizumab to the Standard of Care Reduces Mortality in Severe COVID-19: A Systematic Review and Meta-Analysis
(2020-10-02)Introduction: Tocilizumab (TCZ) is an anti-interleukin-6 antibody that has been used for the treatment of severe coronavirus disease 2019 (COVID-19). However, concrete evidence of its benefit in reducing mortality in severe ... -
Mental health outcomes of adults hospitalized for COVID-19: A living rapid review
(2020-10-01)Scope: This rapid review compares the prevalence of mental health disorders among adults who have been hospitalized for COVID-19 to relevant comparison groups, assesses whether the prevalence of mental health disorders ... -
The Prognostic Value of Thrombocytopenia in COVID-19 Patients; a Systematic Review and Meta-Analysis
(2020-09-22)Introduction: Multiple lines of evidence have attested that decreased numbers of platelets may serve as a surrogate marker for poor prognosis in a wide range of infectious diseases. Thus, to provide a well-conceptualized ... -
COVID-19 pandemic and maternal mental health: a systematic review and meta-analysis
(2020-11-01)Objective: To evaluate the effect of the COVID-19 pandemic on anxiety and depression of women during pregnancy and perinatal period. Methods: We systematically searched online databases to identify any report on maternal ... -
Clinical Characteristics and Outcomes of COVID-19–Infected Cancer Patients: A Systematic Review and Meta-Analysis
(2020-11-02)Background: Previous studies have indicated coronavirus disease 2019 (COVID-19) patients with cancer have a high fatality rate. Methods: We conducted a systematic review of studies that reported fatalities in COVID-19 ... -
Association of active oncologic treatment and risk of death in cancer patients with COVID-19: a systematic review and meta-analysis of patient data
(2020-11-02)Background: Cancer patients suffer from worse coronavirus disease-2019 (COVID-19) outcomes. Whether active oncologic treatment is an additional risk factor in this population remains unclear. Therefore, here we have conducted ...
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