Resources in English
Recent Submissions
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Clinical Characteristics of Asymptomatic and Symptomatic Pediatric Coronavirus Disease 2019 (COVID-19): A Systematic Review
(2020-09)Background and objectives: Characterization of pediatric coronavirus disease 2019 (COVID-19) is necessary to control the pandemic, as asymptomatic or mildly infected children may act as carriers. To date, there are limited ... -
PCR positives: what do they mean?
(2020-09)Contents Is the PCR test sensitive enough?. page 2 Culturing a virus as reference test page 2 Does a PCR “TRUE POSITIVE” mean INFECTIVITY OR VIRULENCE?. page 2 PCR true positives versus infectivity and virulence. page ... -
Olfactory Dysfunction in Coronavirus Disease 2019 Patients: Observational Cohort Study and Systematic Review
(2020-06)Background - Olfactory dysfunction (OD) has been reported in coronavirus disease 2019 (COVID-19). However, there are knowledge gaps about the severity, prevalence, etiology, and duration of OD in COVID-19 patients. Methods ... -
Sinonasal pathophysiology of SARS‐CoV‐2 and COVID‐19: A systematic review of the current evidence
(2020-04-10)Abstract: Objective -The ongoing pandemic of coronavirus disease (2019 coronavirus disease [COVID‐19]), caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2) virus, is highly contagious with high ... -
COVID-19 in otolaryngologist practice: a review of current knowledge
(2020)Abstract: Purpose Otorhinolaryngological manifestations are common symptoms of COVID-19. This study provides a brief and precise review of the current knowledge regarding COVID-19, including disease transmission, clinical ... -
Mortality in hospitalized patients with cancer and coronavirus disease 2019: A systematic review and meta‐analysis of cohort studies
(2020-12-30)Background: Heterogeneous evidence exists on the effect of coronavirus disease 2019 (COVID‐19) on the clinical outcomes of patients with cancer. Methods: A systematic review was performed using the Medline, Embase, and ... -
COVID-19 and ethnicity: A novel pathophysiological role for inflammation
(2020-10)Introduction There have been recent mounting concerns regarding multiple reports stating a significantly elevated relative-risk of COVID-19 mortality amongst the Black and Minority Ethnic (BAME) population. An urgent ... -
Safety at the Time of the COVID-19 Pandemic: How to Keep Our Oncology Patients and Healthcare Workers Safe
(2020-05)The novel coronavirus, SARS-CoV-2, was first detected as a respiratory illness in December 2019 in Wuhan City, China. Since then, coronavirus disease 2019 (COVID-19) has impacted every aspect of our lives worldwide. In a ... -
Threat Assessment Brief: Reinfection with SARS-CoV-2: considerations for public health response
(2020)Cases with suspected or possible reinfection with SARS-CoV-2 have been recently reported in different countries. In many of these cases, it is uncertain if the individual’s Polymerase Chain Reaction (PCR) test remained ... -
COVID-19 testing strategies and objectives
(2020)This document outlines strategies and objectives for sustainable SARS-CoV-2 testing of populations to achieve specific public health objectives in various epidemiological situations. General population-wide testing, as ... -
COVID-19 in children and the role of school settings in transmission - first update
(2020)The aim of this document is to provide an update on the knowledge surrounding the role of children in the transmission of SARS-CoV-2 and the role of schools in the COVID-19 pandemic, based on the experience in the EU from ... -
Evaluating the Efficacy and Safety of the Existing Repurposed Pharmacological Agents for Treating COVID-19: A Meta-analysis and Systematic Review of Clinical Trials
(2020-11)Purpose: The present study systematically searched important medical databases, assessed the quality of available pieces of evidence, and performed a meta-analysis to test the efficacy of different therapeutic options ... -
Current Evidence of Interleukin-6 Signaling Inhibitors in Patients With COVID-19: A Systematic Review and Meta-Analysis
(2020-12-15)Background: Interleukin-6 (IL-6) is known to be detrimental in coronavirus disease 2019 (COVID-19) because of its involvement in driving cytokine storm. This systematic review and meta-analysis aimed to assess the safety ... -
Comparative efficacy and safety of pharmacological interventions for the treatment of COVID-19: A systematic review and network meta-analysis
(2020-12-30)Background: Numerous clinical trials and observational studies have investigated various pharmacological agents as potential treatment for Coronavirus Disease 2019 (COVID-19), but the results are heterogeneous and sometimes ... -
Cell-based therapies for COVID-19: A living, systematic review
(2020-12-17)Objective: This living, systematic review aims to provide a timely, rigorous, and continuously updated summary of the available evidence on the role of cell-based therapies in the treatment of patients with COVID-19. Data ... -
Aerobic exercises recommendations and specifications for patients with COVID-19: a systematic review
(2020)OBJECTIVE: This review was conducted to systematically analyze the effects of aerobic exercise on immunological biomarkers to provide safe aerobic exercise recommendations and specifications for patients with COVID-19. ... -
The use of convalescent plasma for pediatric patients with SARS-CoV-2: A systematic literature review
(2020-12-23)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the virus that causes coronavirus disease 2019 (COVID-19), a severe illness leading to pneumonia, multiorgan failure, and death. With this study, we performed ... -
The Effect of Metformin Consumption on Mortality in Hospitalized COVID-19 patients: a systematic review and meta-analysis
(2020-11-11)Background and aims: Diabetes is one of the most common comorbidities, and it is associated with poorer outcomes in patients with coronavirus disease 2019 (COVID-19). Preliminary findings showed that mortality was reduced ... -
State of Emergency Curfew continues from 13th May – 9:00 p.m. to Friday June 12, 2020 – 5:00 a.m. Official Guidelines
(2020-05-14)• The government of Antigua and Barbuda has declared a State of Emergency in an effort to curb the spread of the Coronavirus – COVID 19 • A curfew has been enacted from Wednesday 13th May – 9:00 p.m. to Friday June 12, ...
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