| dc.contributor.author | Pan American Health Organization | |
| dc.date.accessioned | 2020-07-01T21:00:07Z | |
| dc.date.available | 2020-07-01T21:00:07Z | |
| dc.date.issued | 2020-06 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12663/1907 | |
| dc.identifier.uri | https://iris.paho.org/handle/10665.2/52235 | |
| dc.description.abstract | [Extract]. Ferritin is a key mediator of immune dysregulation, especially under extreme hyperferritinemia, via direct immune-suppressive and pro-inflammatory effects, contributing to the cytokine storm1. It has been reported that fatal outcomes by COVID-19 are accompanied by cytokine storm syndrome, thereby it has been suggested that disease severity is dependent of the cytokine storm syndrome2. Many individuals with diabetes exhibit elevated serum ferritin levels3-5, and it is known that they face a higher probability to experience serious complications from COVID-196. On this basis, we briefly review evidence supporting the hypothesis that ferritin levels might be a crucial factor influencing the severity of COVID-19. | |
| dc.language | English | |
| dc.subject | Infecctious Diseases | |
| dc.subject | COVID-19 | |
| dc.subject | Coronavirus | |
| dc.title | Ferritin levels and COVID-19 | |
| eihealth.country | Regional, Americas (PAHO/OPS) | |
| eihealth.category | Infection prevention and control, including health care workers protection | |
| eihealth.type | WHO/PAHO Guidance | |
| eihealth.maincategory | Save Lives / Salvar Vidas | |
