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Convalescent plasma treatment of severe COVID-19: A matched control study
(2020-05-22)Background Since December 2019, Coronavirus Disease 2019 (COVID-19) has become a global pandemic, causing mass morbidity and mortality. Prior studies in other respiratory infections suggest that convalescent plasma transfusion ... -
Trends of SARS-CoV-2 infection worldwide: Role of population density, age structure, and climate on transmission and case fatality
(2020-05-22)Introduction The disease transmission pattern of COVID19 is highly heterogeneous, which suggests that the pandemic maybe driven by complex factors, which may include habitat suitability, region specific human mobility, and ... -
The potential impact of the COVID-19 pandemic on tuberculosis: a modelling analysis
(2020-05-20)Background Routine services for tuberculosis (TB) are being disrupted by stringent lockdowns against the novel SARS-CoV-2 virus. We sought to estimate the potential long-term epidemiological impact of such disruptions on ... -
Neutralizing Antibodies Responses to SARS-CoV-2 in COVID-19 Inpatients and Convalescent Patients
(2020-04-23)Background. COVID-19 is a pandemic with no specific antiviral treatments or vaccines. The urgent needs for exploring the neutralizing antibodies from patients with different clinical characteristics are emerging. Methods. ... -
Saliva is more sensitive for SARS-CoV-2 detection in COVID-19 patients than nasopharyngeal swabs
(2020-04-22)Rapid and accurate SARS-CoV-2 diagnostic testing is essential for controlling the ongoing COVID-19 pandemic. The current gold standard for COVID-19 diagnosis is real-time RT-PCR detection of SARS-CoV-2 from nasopharyngeal ... -
Large-scale implementation of pooled RNA-extraction and RT-PCR for SARS-CoV-2 detection
(2020-05-07)Testing for active SARS-CoV-2 infection is a fundamental tool in the public health measures taken to control the COVID-19 pandemic. Due to the overwhelming use of SARS-CoV-2 RT-PCR tests worldwide, availability of test ... -
COVID-19 pandemic and troponin: indirect myocardial injury, myocardial inflammation or myocarditis?
(2020-07-10)The initial mechanism for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection is the binding of the virus to the membrane-bound form of ACE2, which is mainly expressed in the lung. Since the heart and ... -
Evidence-Based, Cost-Effective Interventions To Suppress The COVID-19 Pandemic: A Systematic Review
(2020-06-15)Background: In an unparalleled global response, during the COVID-19 pandemic, 90 countries asked 3.9 billion people to stay home. Yet some countries avoided lockdowns and focused on other strategies, like contact tracing ... -
COVID-19 and anosmia in Tehran, Iran
(2020-04-23)Patients with acute olfactory disorders typically present to the otolaryngologist with both acute hyposmia and less often with anosmia. With the onset of COVID-19 we have noticed an increase in the number of patients who ... -
Laparoscopic Surgery and the debate on its safety during COVID-19 pandemic: A systematic review of recommendations
(2020-08-11)Introduction: The transmission of COVID-19 virus since the outbreak of viral pneumonia due to SARS-CoV-2 gave rise to protective operative measures. Aerosol generating procedures such as laparoscopic surgery are known to ...