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Potential Rapid Diagnostics, Vaccine and Therapeutics for 2019 Novel Coronavirus (2019-nCoV): A Systematic Review
(2020-02-26)Rapid diagnostics, vaccines and therapeutics are important interventions for the management of the 2019 novel coronavirus (2019-nCoV) outbreak. It is timely to systematically review the potential of these interventions, ... -
Non-severe vs severe symptomatic COVID-19: 104 cases from the outbreak on the cruise ship “Diamond Princess” in Japan
(2020-03-20)Background: The ongoing outbreak of 2019 novel coronavirus disease (COVID-19) is a global threat. Clarifying its clinical features such as risk factors for disease progression is a pressing issue. We analyzed the difference ... -
Potential interventions for novel coronavirus in China: A systematic review
(2020-02-04)An outbreak of a novel coronavirus (COVID‐19 or 2019‐CoV) infection has posed significant threats to international health and the economy. In the absence of treatment for this virus, there is an urgent need to find alternative ... -
Coronavirus in pregnancy and delivery: rapid review
(2020-03-17)OBJECTIVES: Person-to-person spread of COVID-19 in the UK has now been confirmed. There are limited case series reporting the impact on women affected by coronaviruses (CoV) during pregnancy. In women ... -
Extracorporeal membrane oxygenation (ECMO) for patients with acute respiratory failure: Uncertain if it is better or worse than conventional lung support
(2020-03-18)What is this? Some patients with COVID-19 will become critically ill and need help with their breathing. Extracorporeal membrane oxygenation (ECMO) is a form of life support that targets the heart and lungs and which might ... -
High levels of PEEP are not better than low levels for reducing mortality in adult ICU patients with acute respiratory distress syndrome (ARDS) or acute lung injury (ALI)
(2020-03-18)What is this? Some patients with COVID-19 will develop acute respiratory distress syndrome (ARDS) or acute lung injury (ALI) and need help with their breathing. This might be provided by mechanical ventilation (MV) in an ... -
Drugs for treating acute respiratory distress syndrome (ARDS) in critically ill patients
(2020-03-16)What is this? Some patients with COVID-19 will develop acute respiratory distress syndrome (ARDS) and need help with their breathing. ARDS is caused by direct or indirect injury to the lungs and about 40% of people with ... -
Clinical Features and Chest CT Manifestations of Coronavirus Disease 2019 (COVID-19) in a Single-Center Study in Shanghai, China
(2020-02-27)OBJECTIVE. Confronting the new coronavirus infection known as coronavirus disease 2019 (COVID-19) is challenging and requires excluding patients with suspected COVID-19 who actually have other diseases. The purpose of this ... -
Ethics guidance on key issues raised by the novel coronavirus disease (COVID-19) pandemic, 16 March 2020
(2020-03-18)Health authorities are tasked with protecting the health of the population and responding to public health emergencies. An adequate health response to public health emergencies, such as the current WHO-declared COVID-19 ... -
Honey eases acute cough in children
(2020-03-23)What is this? Most people with COVID-19 will develop a persistent cough. Honey is used to ease cough in children. In this Cochrane systematic review, the authors searched for randomised trials of the effects of honey for ...