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dc.contributor.authorAngulo, Marco Tulio et al.
dc.date.accessioned2020-06-19T18:12:59Z
dc.date.available2020-06-19T18:12:59Z
dc.date.issued2020-05-21
dc.identifier.urihttps://doi.org/10.1101/2020.05.19.20107268en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12663/1805
dc.description.abstractTo mitigate the COVID-19 pandemic, much emphasis exists on implementing non-pharmaceutical interventions to keep the reproduction number below one. But using that objective ignores that some of these interventions, like bans of public events or lockdowns, must be transitory and as short as possible because of their significative economic and societal costs. Here we derive a simple and mathematically rigorous criterion for designing optimal transitory non-pharmaceutical interventions. We find that reducing the reproduction number below one is sufficient but not necessary. Instead, our criterion prescribes the required reduction in the reproduction number according to the maximum health services' capacity. To explore the implications of our theoretical results, we study the non-pharmaceutical interventions implemented in 16 cities during the COVID-19 pandemic. In particular, we estimate the minimal reduction of the contact rate in each city that is necessary to control the epidemic optimally. We also compare the optimal start of the intervention with the start of the actual interventions applied in each city. Our results contribute to establishing a rigorous methodology to guide the design of non- pharmaceutical intervention policies.en_US
dc.languageEnglishen_US
dc.subjectCOVID-19en_US
dc.subjectCoronavirusen_US
dc.subjectOutbreaken_US
dc.subjectEpidemicsen_US
dc.subjectSocial Isolationen_US
dc.subjectCoronavirus Infectionsen_US
dc.titleA simple criterion to design optimal nonpharmaceutical interventions for epidemic outbreaksen_US
eihealth.countryGlobal (WHO/OMS)en_US
eihealth.categoryPublic Health Interventionsen_US
eihealth.typePublished Articleen_US
eihealth.maincategorySlow Spread / Reducir la Dispersiónen_US
dc.relation.ispartofjournalmedRxiven_US


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