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dc.contributor.authorIwasaki, Sumio et al.
dc.date.accessioned2020-06-16T17:21:54Z
dc.date.available2020-06-16T17:21:54Z
dc.date.issued2020-05-24
dc.identifier.urihttps://doi.org/10.1101/2020.05.13.20100206en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12663/1760
dc.description.abstractWe prospectively compared the efficacy of PCR detection of SARS-CoV-2 between paired nasopharyngeal and saliva samples in 76 patients including ten COVID-19 patients. The overall concordance rate of the virus detection between the two samples was 97.4% (95%CI, 90.8-99.7). Viral load was equivalent in COVID-19 patients, but the virus tended to disappear earlier in saliva at convalescent phase compared to nasopharyngeal samples. These results suggest that saliva is a reliable noninvasive alternative to nasopharyngeal swabs and facilitate widespread PCR testing in the face of shortages of swabs and protective equipment without posing a risk to healthcare workers.en_US
dc.languageEnglishen_US
dc.subjectCOVID-19en_US
dc.subjectCoronavirusen_US
dc.subjectBetacoronavirusen_US
dc.subjectPolymerase Chain Reactionen_US
dc.subjectSalivaen_US
dc.subjectNasopharynxen_US
dc.subjectHealth Personnelen_US
dc.subjectPersonal Protective Equipmenten_US
dc.titleComparison of SARS-CoV-2 detection in nasopharyngeal swab and salivaen_US
eihealth.countryGlobal (WHO/OMS)en_US
eihealth.categoryVirus: natural history, transmission and diagnosticsen_US
eihealth.typePublished Articleen_US
eihealth.maincategorySlow Spread / Reducir la Dispersiónen_US
dc.relation.ispartofjournalmedRxiven_US


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