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dc.contributor.authorWang, Bolin
dc.contributor.authorLi, Ruobao
dc.contributor.authorLu, Zhong
dc.contributor.authorHuang, Yan
dc.date.accessioned2020-04-13T23:11:26Z
dc.date.available2020-04-13T23:11:26Z
dc.date.issued2020-04-08
dc.identifier.urihttps://doi.org/10.18632/aging.103000en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12663/1002
dc.description.abstractCurrently, the number of patients with coronavirus disease 2019 (COVID-19) has increased rapidly, but relationship between comorbidity and patients with COVID-19 still not clear. The aim was to explore whether the presence of common comorbidities increases COVID-19 patients’ risk. A literature search was performed using the electronic platforms (PubMed, Cochrane Library, Embase, and other databases) to obtain relevant research studies published up to March 1, 2020. Relevant data of research endpoints in each study were extracted and merged. All data analysis was performed using Stata12.0 software. A total of 1558 patients with COVID-19 in 6 studies were enrolled in our meta-analysis eventually. Hypertension (OR: 2.29, P<0.001), diabetes (OR: 2.47, P<0.001), chronic obstructive pulmonary disease (COPD) (OR: 5.97, P<0.001), cardiovascular disease (OR: 2.93, P<0.001), and cerebrovascular disease (OR:3.89, P=0.002)were independent risk factors associated with COVID-19 patients. The meta-analysis revealed no correlation between increased risk of COVID-19 and liver disease, malignancy, or renal disease. Hypertension, diabetes, COPD, cardiovascular disease, and cerebrovascular disease are major risk factors for patients with COVID-19. Knowledge of these risk factors can be a resource for clinicians in the early appropriate medical management of patients with COVID-19.en_US
dc.languageEnglishen_US
dc.subjectCOVID-19en_US
dc.subjectCoronavirusen_US
dc.subjectInfectious Diseasesen_US
dc.subjectComorbidityen_US
dc.subjectMeta-Analysisen_US
dc.subjectRisken_US
dc.titleDoes comorbidity increase the risk of patients with COVID-19: evidence from meta-analysisen_US
eihealth.countryOthersen_US
eihealth.categoryClinical characterization and managementen_US
eihealth.typePublished Articleen_US
eihealth.maincategorySave Lives / Salvar Vidasen_US
dc.relation.ispartofjournalAgingen_US


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