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Coronavirus Disease 2019 in elderly patients: characteristics and prognostic factors based on 4-week follow-up
(2020-03-15)[Abstract]. Objective: To investigate the characteristics and prognostic factors in the elderly patients with COVID-19. Methods: Consecutive cases over 60 years old with COVID-19 in Renmin Hospital of Wuhan University from ... -
Pivotal Role of Convalescent Plasma in Managing Emerging Infectious Diseases
(2020-04-02)Infectious diseases remain one of the top 10 global health threats as announced by the World Health Organization. The emergence of new pathogens for which there is no effective treatment has redrawn the attention to the ... -
Computational inference of selection underlying the evolution of the novel coronavirus, SARS-CoV-2
(2020-04-01)The novel coronavirus (SARS-CoV-2) recently emerged in China is thought to have a bat origin, as its closest known relative (BatCoV RaTG13) was described in horseshoe bats. We analyzed the selective events that accompanied ... -
Household Transmission of SARS-CoV-2
(2020-03-21)[Abstract]. Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused an epidemic in China and many other countries. Many infected clusters have been found within familial households, but the data ... -
Full-genome sequences of the first two SARS-CoV-2 viruses from India
(2020)Background & objectives : Since December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has globally affected 195 countries. In India, suspected cases were screened for SARS-CoV-2 as per the advisory ... -
Biorisk assessment for infrastructure & biosafety requirements for the laboratories providing coronavirus SARS-CoV-2/(COVID-19) diagnosis
(2020)Novel coronavirus infection [coronavirus disease 2019 (COVID-19)] has spread to more than 203 countries of various regions including Africa, America, Europe, South East Asia and Western Pacific. The WHO had declared COVID-19 ... -
Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency
(2020-04-13)Effective treatments for coronavirus disease 2019 (COVID-19) are urgently needed to control this current pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Replication of SARS-CoV-2 depends ... -
Evidence Based Management Guideline for the COVID-19 Pandemic - Review article
(2020-04-11)COVID-19 has now been declared a pandemic. To date, COVID-19 has affected over 944,181 people worldwide, resulting in over 47,312 reported deaths. Numerous preventative strategies and non-pharmaceutical interventions have ... -
COVID-19 Pandemic: Experiences in China and implications for its prevention and treatment worldwide
(2020)The outbreak of COVID-19 due to SARS-CoV-2 originally emerged in Wuhan in December, 2019. As of March 22, 2020, the disease had spread to 186 countries, with at least 305,275 confirmed cases. Although there has been a ... -
Risk factors for severity and mortality in adult COVID-19 inpatients in Wuhan
(2020)Background: In December 2019, the coronavirus disease 2019 (COVID-19) outbreak occurred in Wuhan. Data on the clinical characteristics and outcomes of patients with severe COVID-19 are limited. Objective: We sought to ...
