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Hydroxychloroquine and Azithromycin as a Treatment of COVID-19: Results of an Open-Label Non-Randomized Clinical Tria
(2020-03-20)Chloroquine and hydroxychloroquine have been found to be efficient on SARS-CoV-2, and reported to be efficient in Chinese COV-19 patients. We evaluate the role of hydroxychloroquine on respiratory viral loads. Patients and ... -
Chloroquine and hydroxychloroquine: Current evidence for their effectiveness in treating COVID-19
(2020-03-25)Verdict: Several in vitro studies report antiviral activity of chloroquine and hydroxychloroquine against SARS-CoV-2. In vivo data, although promising, is currently limited to one study with considerable limitations. On ... -
In vitro testing of Hydroxychloroquine and Azithromycin on SARS-CoV-2 shows synergistic effect
(2020-03)Human coronaviruses SARS-CoV-2 appeared at the end of 2019 and led to a pandemic with high morbidity and mortality. As there are currently no effective drugs targeting this virus, drug repurposing represents a short-term ... -
Of Chloroquine and COVID-19
Recent publications have brought attention to the possible benefit of chloroquine, a broadly used antimalarial drug, in the treatment of patients infected by the novel emerged coronavirus (SARS-CoV-2). The scientific ... -
Hydroxychloroquine: a potential ethical dilemma for rheumatologists during the COVID-19 pandemic
(2020-04)Two antimalarial agents, chloroquine (CQ) and hydroxychloroquine (HCQ), have been trusted treatments for a range of rheumatic diseases over the past seventy years [1]. These agents have attracted intense media attention ... -
COVID-19: Chloroquine and hydroxychloroquine research
(2020-04-02)In some countries in the Americas, chloroquine or hydroxychloroquine is readily available, in some cases as an over-the-counter medicine. National authorities should take measures to control the use of these medicines and ... -
COVID-19: A Brief Overview of the Discovery Clinical Trial
(2020-04-10)COVID-19 (coronavirus disease 2019) is a worldwide outbreak of pneumonia and acute respiratory distress syndrome. It is unambiguously linked to the human–human transmission of a novel coronavirus. Mutagenomic analyses ... -
Clinical and microbiological effect of a combination of hydroxychloroquine and azithromycin in 80 COVID-19 patients with at least a six-day follow up: A pilot observational study
(2020-03)Background: We need an effective treatment to cure COVID-19 patients and to decrease virus carriage duration. Methods: We conducted an uncontrolled, non-comparative, observational study in a cohort of 80 relatively mildly ... -
Virological and Clinical Cure in Covid‐19 Patients Treated with Hydroxychloroquine: A Systematic Review and Meta‐Analysis
(2020-04-16)Background: Following the demonstration of efficacy of hydroxychloroquine against SARS‐CoV‐2 in‐vitro, many trials started to evaluate its efficacy in clinical settings. However, no systematic review and meta‐analysis has ... -
Recomendaciones clínicas basadas en evidencias. Coronavirus / COVID-19: Recomendación uso de cloroquina o hidroxicloroquina en personas con COVID-19
(2020)En personas con COVID-19, el Ministerio de Salud de Chile no sugiere utilizar cloroquina o hidroxicloroquina de rutina. Comentario del panel: ►Si bien para la mayoría de los pacientes con COVID-19, se sugiere no utilizar ...