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Early estimation of the case fatality rate of COVID-19 in mainland China: a data-driven analysis
(2020-02-12)An ongoing outbreak of pneumonia caused by a novel coronavirus [severe acute respiratory syndrome coronavirus (SARS-CoV)-2], named COVID-19, hit a major city of China, Wuhan in December 2019 and subsequently spread to other ... -
Detection of 2019 Novel Coronavirus (2019-nCoV) by Real-Time RT-PCR
Background: The ongoing outbreak of the recently emerged novel coronavirus (2019-nCoV) poses a challenge for public health laboratories as virus isolates are unavailable while there is growing evidence that the outbreak ... -
The 2019-new Coronavirus Epidemic: Evidence for Virus Evolution
There is a worldwide concern about the new coronavirus 2019-nCoV as a global public health threat. In this article, we provide a preliminary evolutionary and molecular epidemiological analysis of this new virus. A phylogenetic ... -
Development of Genetic Diagnostic Methods for Novel Coronavirus 2019 (nCoV-2019) in Japan
(2020-02-13)At the end of 2019, pneumonia caused by novel coronavirus 2019 (nCoV) emerged in Wuhan city, China. Many airline travelers moved between Wuhan and Japan at that time, suggesting that Japan is at high risk of invasion by ... -
Systematic review of COVID‐19 in children shows milder cases and a better prognosis than adults
(2020-03-23)Aim: The coronavirus disease 2019 (COVID‐19) pandemic has affected hundreds of thousands of people. Data on symptoms and prognoses in children are rare. Methods: A systematic literature review was carried out to identify ... -
List of Priority Medical Devices in the context of COVID-19 (provisional recommendations, 06 April 2020) 3rd Version
(2020-04-06)Objective of the document: The list of priority medical devices in the context of COVID-19 provides technical descriptions and specifications for the management of patients with suspected and/or confirmed COVID-19 infection ... -
Rapid asymptomatic transmission of COVID-19 during the incubation period demonstrating strong infectivity in a cluster of youngsters aged 16-23 years outside Wuhan and characteristics of young patients with COVID-19: a prospective contact-tracing study
(2020-04)[Abstract]. Background: The outbreak of coronavirus-disease-2019 (COVID-19) has rapidly spread to many places outside Wuhan. Previous studies on COVID-19 mostly included older hospitalized-adults. Little information on ... -
A method to prevent SARS-CoV-2 IgM false positives in gold immunochromatography and enzyme-linked immunosorbent assays
(2020-04-10)[Abstract]. Objective: To investigate the interference factors that lead to false-positive novel coronavirus (SARS-CoV-2) IgM detected using gold immunochromatography assay (GICA) and enzyme-linked immunosorbent assay ... -
Structure of the RNA-dependent RNA polymerase from COVID-19 virus
(2020-04-10)A novel coronavirus (COVID-19 virus) outbreak has caused a global pandemic resulting in tens of thousands of infections and thousands of deaths worldwide. The RNA-dependent RNA polymerase (RdRp, also named nsp12) is the ... -
Serological immunochromatographic approach in diagnosis with SARS-CoV-2 infected COVID-19 patients
(2020-03-26)An outbreak of new coronavirus SARS-CoV-2 was occurred in Wuhan, China and rapidly spread to other cities and nations. The standard diagnostic approach that widely adopted in the clinic is nucleic acid detection by real-time ...