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Differential ventilation using flow control valves as a potential bridge to full ventilatory support during the COVID-19 crisis
(2020-04-21)Background: It has been projected that there will be too few ventilators to meet demand during the COVID-19 (SARS CoV-2) pandemic. Ventilator sharing has been suggested as a crisis standard of care strategy to increase ... -
The production of antibodies for SARS-CoV-2 and its clinical implication
(2020-04-24)Background: Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2), a novel betacoronavirus, has caused an outburst of pneumonia cases in Wuhan, China. We report the production of specific IgM and IgG antibodies after ... -
Rapid identification of SARS-CoV-2-infected patients at the emergency department using routine testing
(2020-04-24)Background: The novel coronavirus disease 19 (COVID-19), caused by SARS-CoV-2, spreads rapidly across the world. The exponential increase in the number of cases has resulted in overcrowding of emergency departments (ED). ... -
Effects of Covid-19 infection during pregnancy and neonatal prognosis: what is the evidence?
(2020-05-19)Background: Little is known about how COVID-19 infection affects pregnant women, as well as about the possibility of vertical transmission or complications in childbirth. This study's aims to assess the current evidence ... -
Predicting mortality due to SARS-CoV-2: A mechanistic score relating obesity and diabetes to COVID-19 outcomes in Mexico
(2020-04-22)BACKGROUND: The SARS-CoV-2 outbreak poses challenge to healthcare systems due to high complication rates in patients with cardiometabolic diseases. Here, we identify risk factors and propose a clinical score to predict ... -
Neutralizing Antibodies Responses to SARS-CoV-2 in COVID-19 Inpatients and Convalescent Patients
(2020-04-23)Background. COVID-19 is a pandemic with no specific antiviral treatments or vaccines. The urgent needs for exploring the neutralizing antibodies from patients with different clinical characteristics are emerging. Methods. ... -
Occurrence and Timing of Subsequent SARS-CoV-2 RT-PCR Positivity Among Initially Negative Patients
(2020-05-08)Background: SARS-CoV-2 reverse transcriptase polymerase chain reaction (RT-PCR) testing remains the cornerstone of laboratory-based identification of patients with COVID-19. As the availability and speed of SARS-CoV-2 ... -
Lung ultrasound findings in patients with novel SARS-CoV2
(2020-05-21)Background: Over 2 million people worldwide have been infected with Severe Acute Respiratory Distress Syndrome Corona Virus 2 (SARS CoV2). Lung ultrasound has been proposed to diagnose and it. However, little is known about ... -
Characterization of Patients Who Return to Hospital Following Discharge from Hospitalization For COVID-19
(2020-05-22)Background: Data on patients with coronavirus disease 2019 (COVID-19) who return to hospital after discharge are scarce. Characterization of these patients may inform post-hospitalization care. Methods and Findings: ... -
SARS-CoV-2 pandemic in Italy: ethical and organizational considerations
(2020-05-25)The current SARS-CoV-2 pandemic is still raging in Italy. The country is currently plagued by a huge burden of virus relatedcases and deaths. So far, the disease has highlighted a number of problems, some in common with ...