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Potential Rapid Diagnostics, Vaccine and Therapeutics for 2019 Novel Coronavirus (2019-nCoV): A Systematic Review
(2020-02-26)Rapid diagnostics, vaccines and therapeutics are important interventions for the management of the 2019 novel coronavirus (2019-nCoV) outbreak. It is timely to systematically review the potential of these interventions, ... -
What makes health systems resilient against infectious disease outbreaks and natural hazards? Results from a scoping review.
(2019-10-19)BACKGROUND:The 2014-2016 Ebola outbreak was a wake-up call regarding the critical importance of resilient health systems. Fragile health systems can become overwhelmed during public health crises, further exacerbating the ... -
Effectiveness of Masks and Respirators Against Respiratory Infections in Healthcare Workers: A Systematic Review and Meta-Analysis
(2017-08-07)This systematic review and meta-analysis quantified the protective effect of facemasks and respirators against respiratory infections among healthcare workers. Relevant articles were retrieved from Pubmed, EMBASE, and Web ... -
Health care costs of influenza-related episodes in high income countries: A systematic review
(2018-09-07)INTRODUCTION: This study systematically reviews costing studies of seasonal influenza-like illness (ILI) in high-income countries. Existing reviews on the economic impact of ILI do not report information on drug consumption ... -
Non-severe vs severe symptomatic COVID-19: 104 cases from the outbreak on the cruise ship “Diamond Princess” in Japan
(2020-03-20)Background: The ongoing outbreak of 2019 novel coronavirus disease (COVID-19) is a global threat. Clarifying its clinical features such as risk factors for disease progression is a pressing issue. We analyzed the difference ... -
Potential interventions for novel coronavirus in China: A systematic review
(2020-02-04)An outbreak of a novel coronavirus (COVID‐19 or 2019‐CoV) infection has posed significant threats to international health and the economy. In the absence of treatment for this virus, there is an urgent need to find alternative ... -
Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV2)
(2020-03-16)Estimation of the prevalence and contagiousness of undocumented novel coronavirus (SARS-CoV2) infections is critical for understanding the overall prevalence and pandemic potential of this disease. Here we use observations ... -
Additional steroid treatment for patients with influenza who are critically ill: Uncertain whether beneficial or harmful
(2020-03-16)What is this? Corticosteroids are widely used for people with severe influenza, but there is uncertainty about their potential benefits or harms. Corticosteroids have shown evidence of benefit in sepsis and related conditions, ... -
Surge Capacity of Hospitals in Emergencies and Disasters With a Preparedness Approach: A Systematic Review
(2017-05-07)OBJECTIVE: Surge capacity is one of the most important components of hospital preparedness for responding to emergencies and disasters. The ability to provide health and medical care during a sudden increase in the number ... -
Epidemiologic and Clinical Characteristics of 91 Hospitalized Patients with COVID-19 in Zhejiang, China: A retrospective, multi-centre case series.
(2020-03-17)Background: Recent studies have focused initial clinical and Epidemiologic characteristics on the COVID-19, mainly revealing situation in Wuhan, Hubei. Aim: To reveal more data on the epidemiologic and clinical characteristics ...